• Khyati Raina

    M.Sc. Stem Cell and Tissue Engineering, Panjab University, Chandigarh, India

    Awards:

      • Awarded a travel grant for "Training program in Generation and Maintenance of Human iPS cells" organized by "The Accelerating the Application of Stem Cell Technology in Human Diseases (ASHD)" program supported by the Department of Biotechnology (DBT), Government of India, and The Centre for iPS Cell Research and Application (CiRA), Kyoto University, Japan, from 20th to 26th November 2019.

      Weblink: https://www.ncbs.res.in/adbs/blog/indo-japan-collaboration-program-enables-special-training-indian-researchers-ipsc-technology

    • • Awarded a travel grant by Science and Engineering Research Board-Department of Science and Technology (SERB-DST), Government of India for participating in the International meeting organized by "International Society for Stem Cell Research (ISSCR)” from 14th to 17th June, 2023 at Boston, Massachusetts, USA.

      • Workshop:

      • Participated in a workshop on "CRISPR-Cas9 based precise genome editing" organized and hosted by "CSIR-Institute of Genomics and Integrative Biology" at New Delhi, India from 8th to 12th April, 2019.

      Conference/Symposium:

      • Participated in India|EMBO symposium on "Regulatory epigenomics: From large data to useful models" with a poster at Chennai, India from 10th to 13th March, 2019.

      Publications ▼

      Publications (from SCERM Lab):

        • Raina K, Joshi G, Modak K, Premkumar C, Priyanka S, Rajesh P, Velayudhan SR, Thummer RP (2023). Generation and characterization of induced pluripotent stem cell line IITGi001-A derived from adult human primary dermal fibroblasts. Stem Cell Research. https://doi.org/10.1016/j.scr.2023.103159

        • Dey, C., Raina K, Thummer, R.P. (2023). Production of a Bioactive Recombinant Human UTF1 Protein from E. coli. Healthcare Research and Related Technologies. NERC 2022. In: Pandey, L.M., Gupta, R., Thummer, R.P., Kar, R.K. (eds) Springer, Singapore. https://doi.org/10.1007/978-981-99-4056-1_4

        • Subhendu SS, Bora A, Golder A, Raina K, Haridhasapavalan KK, Thummer RP (2022) Gelatin-PVA-AgNPs triad composite as wound healing hydrogel with wounded skin surface protective efficiency, SSRN Electronic Journal, http://dx.doi.org/10.2139/ssrn.4219683 (Elsevier).

        • Banerjee K, Bhattacherjee D, Raina K, Thummer RP, Bhabak KP (2022) Benzimidazole-based ionic and non-ionic organoselenium compounds: innovative synthetic strategies, structural characterization and preliminary anti-proliferative activities. New Journal of Chemistry, 46(24):11910-26. 10.1039/D2NJ01322C (Royal Society of Chemistry).

        • Bhattacherjee D, Raina K, Mandal T K, Thummer RP, Bhabak KP (2022) Targeting Wnt/β-catenin Signaling Pathway in Triple-negative Breast Cancer by Benzylic Organotrisulfides: Contribution of the Released Hydrogen Sulfide towards Potent Anti-Cancer Activity. Free Radical Biology and Medicine.

        • Sundaravadivelu PK, Raina K, Thool M, Ray A, Joshi JM, Kaveeshwar V, Sudhagar S, Lenka N, Thummer RP (2021) Tissue-restricted Stem Cells as Starting Cell Source for Efficient Generation of Pluripotent Stem Cells: An Overview. In: Turksen K. (eds) Cell Biology and Translational Medicine. Advances in Experimental Medicine and Biology (Springer Nature). https://doi.org/10.1007/5584_2021_660

        • Ray A*, Joshi JM*, Sundaravadivelu PK*, Raina K, Lenka N, Kaveeshwar V, Thummer RP (2021) An overview on promising somatic cell sources utilized for the efficient generation of induced pluripotent stem cells. Stem Cell Reviews and Reports. https://doi.org/10.1007/s12015-021-10200-3 *Equal contribution.

        • Dey C*, Raina K*, Thool M*, Adhikari P, Haridhasapavalan KK, Sundaravadivelu PK, Venkatesan V, Gogoi R, Sudhagar S, Thummer RP (2021) Auxiliary pluripotency-associated genes and their contributions in the generation of induced pluripotent stem cells. Molecular Players in IPSC Technology, Volume 12. Elsevier: Academic Press. ISBN: 9780323900591 *Equal contribution.

        • Raina K, Dey C, Thool M, Sudhagar S, Thummer RP (2021) An insight into the role of UTF1 in development, stem cells, and cancer. Stem Cell Reviews and Reports. doi: 10.1007/s12015-021-10127-9 (Springer Nature).

        • Haridhasapavalan KK, Sundaravadivelu PK, Bhattacharyya S, Harsh Ranjan S, Raina K, Thummer RP (2021) Generation of cell-permeant recombinant human transcription factor GATA4 from E. coli. Bioprocess and Biosystems Engineering, 44(6), 1131-1146. https://doi.org/10.1007/s00449-021-02516-8 (Springer Nature).

        • Dey C*, Raina K*, Haridhasapavalan KK*, Thool M*, Sundaravadivelu PK, Adhikari P, Gogoi R, Thummer RP (2021) An Overview of Reprogramming Approaches to Derive Integration-free Induced Pluripotent Stem Cells for Prospective Biomedical Applications. Recent Advances in iPSC Technology, Volume 5 in Advances in Stem Cell Biology. Elsevier: Academic Press. ISBN: 9780128222317. *Equal contribution.

        • Haridhasapavalan KK*, Raina K*, Dey C*, Adhikari P, Thummer RP (2020) An Insight into Reprogramming Barriers to iPSC Generation. Stem Cell Rev and Rep. 16(1): 56-81. doi: 10.1007/s12015-019-09931-1 (Springer Nature). *Equal contribution

        • Dey S, Patel A, Raina K, Pradhan N, Biswas O, Thummer RP$, Manna D (2020) Stimuli-Responsive Anticancer Drug Delivery System with Inherent Antibacterial Activities. Chemical Communications. 56(11): 1661-1664. doi:10.1039/c9cc08834b. $ Corresponding Author

        Publications (from other Labs):

        • Mahajan N, Raina K, Gupta A (2019) High fructose induced adipogenesis and inhibitory potential of tigonelline on murine mesenchymal stem cells: a morphological study. IJPSR, 2019; Vol.10(2):528-536.

    Meeting with Prof. Shinya Yamanaka (Nobel Laureate in Physiology or Medicine 2012) by "Accelerating the applications of Stem cell technology in Human Diseases (ASHD)" program supported by Department of Biotechnology (DBT), Government of India and the Centre for iPS cell Research and Application (CiRA), Kyoto University, Japan.


PhD Student

Year of joining: January, 2018
Research Project: Investigating the role of human UTF1 in reprogramming, self-renewal and differentiation using a CRISPR/Cas toolbox
Email ID: raina.khyati@iitg.ac.in
Research Gate ID


PhD Student

Year of joining:  Jan, 2021
Research Project: Genome stability and cell reprogramming
Email ID: p.sundaravadivelu@iitg.ac.in
PMRF Website: http://www.iitg.ac.in/stud/p.sundaravadivelu
Research Gate ID

  • Pradeep Kumar S

    M.Tech Biotechnology, Indian Institute of Technology Guwahati, Guwahati, Assam, India

    Awards:

    • Awarded "Prime Minister Research Fellowship (PMRF)" by Ministry of Education, Government of India, for a period of four years from January 2021 to December 2024 with a research grant of 8 lakhs.

    Publications ▼

    Publications (from SCERM Lab):

    • Chaudhari, H., Kulkarni, R., Sundaravadivelu, P. K., Thummer, R. P., & Bhuyan, M. K. (2024). Dimensionality reduction technique based phase aberration compensation and spurious fringe removal in off-axis digital holographic microscopy. Optics and Lasers in Engineering, 172, 107853.

    • Chaudhari, H., Kulkarni, R., Sundaravadivelu, P. K., Thummer, R. P., & Bhuyan, M. K. (2024). Digital hologram reconstruction algorithm based on the Fractional Fourier transform in non-telecentric digital holographic microscopy. Optics Letters, 49(2), 182-185.

    • Chetia, M., Sarkar, T., Yadav, M., Dey, C., Sundaravadivelu, P. K., Thummer, R. P., & Chatterjee, S. (2024). Tuning of hydrophobic–hydrophilic balance for the development of a salt-tolerant and protease-resistant lipopeptide AMP. New Journal of Chemistry, 48(6), 2764-2777.

    • Sarkar, T., Ghosh, S., Sundaravadivelu, P. K., Pandit, G., Debnath, S., Thummer, R. P., ... & Chatterjee, S. (2024). Mechanism of Protease Resistance of D-Amino Acid Residue Containing Cationic Antimicrobial Heptapeptides. ACS Infectious Diseases.

    • Haridhasapavalan KK, Sundaravadivelu PK, Voorkara U, Kaveeshwar V, Thummer RP (2023) Generation of recombinant version of a bioactive human MEF2C transcription factor from E. coli, Healthcare Research and Related Technologies - Proceedings of NERC 2022 (Springer Nature).

    • Haridhasapavalan, K. K., Sundaravadivelu, P. K., Joshi, N., Das, N. J., Mohapatra, A., Voorkara, U., ... & Thummer, R. P. (2022). Generation of a recombinant version of a biologically active cell-permeant human HAND2 transcription factor from E. coli. Scientific Reports, 12(1), 16129.

    • Haridhasapavalan, K. K., Sundaravadivelu, P. K., Voorkara, U., Kaveeshwar, V., & Thummer, R. P. (2022). Generation of Recombinant Version of a Bioactive Human MEF2C Transcription Factor from E. coli. In North-East Research Conclave (pp. 3-27). Singapore: Springer Nature Singapore.

    • Haridhasapavalan KK, Sundaravadivelu PK, Joshi N, Das NJ, Mohapatra A, Voorkara U, Kaveeshwar V, Thummer RP (2022) Generation of a recombinant version of a biologically active cell-permeant human HAND2 transcription factor from E. coli, Scientific Reports, 10.1038/s41598-022-19745-w (Springer Nature).

    • Thool M, Sundaravadivelu PK, Sudhagar S, Thummer RP (2022) A Comprehensive Review on the Role of ZSCAN4 in Embryonic Development, Stem Cells, and Cancer. Stem Cell Reviews and Reports. Jun 23:1-7. (Springer Nature)

    • Deori NM, Infant T, Sundaravadivelu PK, Thummer RP, Nagotu S (2022) Pex30 undergoes phosphorylation and regulates peroxisome number in Saccharomyces cerevisiae. Molecular Genomics and Genetics. (Springer Nature)

    • Sundaravadivelu PK, Raina K, Thool M, Ray A, Joshi JM, Kaveeshwar V, Sudhagar S, Lenka N, Thummer RP (2021) Tissue-restricted Stem Cells as Starting Cell Source for Efficient Generation of Pluripotent Stem Cells: An Overview. In: Turksen K. (eds) Cell Biology and Translational Medicine. Advances in Experimental Medicine and Biology (Springer Nature).

    • Ray A*, Joshi JM*, Sundaravadivelu PK*, Raina K, Lenka N, Kaveeshwar V, Thummer RP (2021) An overview on promising somatic cell sources utilized for the efficient generation of induced pluripotent stem cells. Stem Cell Reviews and Reports. (Springer Nature) *Equal contribution.

    • Dey C*, Raina K*, Thool M*, Adhikari P, Haridhasapavalan KK, Sundaravadivelu PK, Venkatesan V, Gogoi R, Sudhagar S, Thummer RP (2021) Auxiliary pluripotency-associated genes and their contributions in the generation of induced pluripotent stem cells. Molecular Players in IPSC Technology, Volume 12. Elsevier: Academic Press. ISBN: 9780323900591 *Equal contribution, Invited Book Chapter.

    • Dey C*, Raina K*, Haridhasapavalan KK*, Thool M*, Sundaravadivelu PK, Adhikari P, Gogoi R, Thummer RP (2021) An Overview of Reprogramming Approaches to Derive Integration-free Induced Pluripotent Stem Cells for Prospective Biomedical Applications. Recent Advances in iPSC Technology, Volume 5 in Advances in Stem Cell Biology. Elsevier: Academic Press. ISBN: 9780128222317. *Equal contribution, Invited Book Chapter.

    • Haridhasapavalan KK, Sundaravadivelu PK, Bhattacharyya S, Harsh Ranjan S, Raina K, Thummer RP (2021) Generation of cell-permeant recombinant human transcription factor GATA4 from E. coli. Bioprocess and Biosystems Engineering, 44(6), 1131-1146. (Springer Nature)

    • Narayan G, Sundaravadivelu PK, Agrawal A, Gogoi R, Nagotu S, Thummer RP (2021) Soluble expression, purification, and secondary structure determination of human PDX1 transcription factor. Protein Expression and Purification, 180: 105807. (Elsevier)

    • Haridhasapavalan KK*, Sundaravadivelu PK*, Thummer RP (2020) Codon Optimization, Cloning, Expression, Purification, and Secondary Structure Determination of Human ETS2 Transcription Factor. Molecular Biotechnology, 62(10), 485-494. https://doi.org/10.1007/s12033-020-00266-8 (Springer Nature). *Equal contribution.

Atreyee Borthakur

M.Sc Biomedical Genetics, Vellore Institute of Technology, Vellore, Tamil Nadu, India

Awards:

  • Awarded "Prime Minister Research Fellowship (PMRF)" by Ministry of Education, Government of India, for a period of four years from January 2021 to December 2024 with a research grant of 8 lakhs.

Publications ▼

Publications (from SCERM lab):

  • Haridhasapavalan KK, Borthakur A, Thummer RP (2023) Direct cardiac reprogramming: Current status and future prospects. Sub-series: Cell Biology and Translational Medicine. Series: Advances in Experimental Medicine and Biology (Springer Nature), https://doi.org/10.1007/5584_2022_760 (IF: 3.650).

Publications (from other labs):

  • Borthakur A, Prabhu YD, Gopalakrishnan AV (2020). Role of IL-6 signalling in polycystic ovarian syndrome associated inflammation. Journal of Reproductive Immunology. Sep 1;141:103155. https://doi.org/10.1016/j.jri.2020.103155 (Science Direct).

    Prabhu YD, Borthakur A, Subeka AG, Vellingiri B, Gopalakrishnan AV (2021) Increased pro-inflammatory cytokines in ovary and effect of γ-linolenic acid on adipose tissue inflammation in a polycystic ovary syndrome model. Journal of Reproductive Immunology. Aug 1;146:103345. https://doi.org/10.1016/j.jri.2021.103345 (Science Direct).

PhD Student

Year of joining: Jan, 2022

Research Project: Cell Therapy for Cardiovascular diseases

  • Email ID: atreyee@iitg.ac.in
    • Research Gate ID
    PhD Student

    Year of joining: July, 2023
    Research Project: blank
    Email ID: harsh.vsingh@iitg.ac.in
    Research Gate ID

    • Harsh Vikram Singh

      M.Sc in Life Sciences, Central University of Punjab, Bathinda, Punjab, India

      Publications ▼

      Publications (from SCERM Lab):

      Publications (from other Lab):

      • Malayil, R., Chhichholiya, Y., Vasudeva, K., Singh, H. V., Singh, T., Singh, S., & Munshi, A. (2023) Oncogenic metabolic reprogramming in breast cancer: focus on signaling pathways and mitochondrial genes. Medical Oncology, 40(6), 174.

      • Chhichholiya, Y., Singh, H. V., Singh, S., & Munshi, A. (2024) Genetic variations in tumor-suppressor miRNA-encoding genes and their target genes: focus on breast cancer development and possible therapeutic strategies. Clinical and Translational Oncology, 26(1), 1-15.

      • Bhatti, G. K., Singh, H. V., Sharma, E., Sehrawat, A., Mishra, J., Navik, U., ... & Bhatti, J. S. (2023) Protective role of natural products and bioactive compounds in multiple sclerosis. In Treatments, Nutraceuticals, Supplements, and Herbal Medicine in Neurological Disorders (pp. 453-482). Academic Press.

      • Chhichholiya, Y., Singh, H. V., Vashistha, R., Singh, S., & Munshi, A. (2023) Deciphering the role of KRAS gene in Oncogenesis: Focus on Signaling pathways, Genetic Alterations in 3’UTR, KRAS specific miRNAs and Therapeutic Interventions.Critical Reviews in Oncology/Hematology, 104250.

    Subham Biswas

    M.Sc, University of Gour Banga - India

    Publications ▼

    Publications (from SCERM lab):

    PhD Student
    Year of joining: July, 2023Research Project: Blank Email ID: Blank target="Blank">Research Gate ID
    Junior Research Fellow

    Year of joining: August, 2023
    Research Project: Generation of integration-free human induced pluripotent stem cells using a novel gene delivery vector
    Email ID: asmita.k@rnd.iitg.ac.in

    • Asmita Karmakar

      M.Sc. Molecular and Human Genetics, Banaras Hindu University, Varanasi, Uttar Pradesh, India

    Mtech Student

    Year of joining: June, 2023
    Research Project: Production of bioactive recombinant human ZSCAN4 protein from E. coli
    Email ID: a.allan@iitg.ac.in
    Research Gate ID

    • M.Tech Student

      Allan Blessing Harison Raj A

      B.Tech Biotechnology, Kamraj College of Engineering and Technology, Tamilnadu, India

      Publications ▼

      Publications (from SCERM Lab):

      Publications (from other Lab):

      • Manibalan, S., Harison Raj, A. B., & Achary, A. (2021). Screening of Atherosclerotic Druggable Targets from the Proteome Network of Differentially Expressed Genes. ASSAY and Drug Development Technologies, 19(5), 290-299.

      Students (as co-supervisor)

    • NAVEEN RAJ M

      B.Tech Biotechnology, MEPCO SChlenk, Engineering college, Tamilnadu, India

      Publications ▼

      Publications (from SCERM Lab):

      Publications (from Other Lab):

      • Mukherjee, P., Raj, N., & Sivaprakasam, S. (2023). Harnessing valorization potential of whey permeate for D-lactic acid production using lactic acid bacteria. Biomass Conversion and Biorefinery, 13(17), 15639-15658.

    PhD student

    Supervisor: Prof. S Senthilkumar

    Year of joining: December, 2022
    Email ID: naveenraj@iitg.ac.in