Dr. Shambojit Roy
Assistant Professor
Key Research Areas :Drug delivery, Biomaterials, Cancer therapeutics, Protein engineering, Microscopy and Imaging
- Phone No: +91 361 258 3533
- Email: shro3435@iitg.ac.in
- Room No: 310
2022
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1. Roy, S., Curry, S. D., Bagot, C. C., Mueller, E. V., Mansouri, A. M., Park, W., Cha, J. N., & Goodwin, A. P. , "Enzyme Prodrug Therapy with Photocrosslinkable anti EGFR Affibodies Conjugated to Upconverting Nanoparticles", ACS Nano, 16, 10, 15873-15883, https://pubs.acs.org/doi/full/10.1021/acsnano.2c02558 [2022] |
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2. Roy, S., Curry, S., Bibbey, M. G., Chapnick, D., Liu, X., Goodwin, A. P., & Cha, J. N. , "Effect of covalent photo-conjugation of affibodies to Epidermal Growth Factor Receptor (EGFR) on cellular quiescence. ", Biotechnology and Bioengineering, 119, 1, 187-198, https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/bit.27964 [2022] |
2021
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1. Ganguly, S., Roy, S., Goodwin, A. P., & Cha, J. N., "Generation of 3D cellular spheroids using DNA modified cell receptors and programmable DNA interactions", Biomaterials Science, 9, 23, 7911-7920, https://pubs.rsc.org/en/content/articlehtml/2021/bm/d1bm01193f [2021] |
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2. Harris, A. W., Roy, S., Ganguly, S., Parameswar, A. V, Lucas, F. W. S., Holewinski, A., Goodwin, A. P., Cha, J. N, "Investigating the use of conducting oligomers and redox molecules in CdS – MoFeP biohybrids", Nanoscale Advances, 3, 1392-1396, https://pubs.rsc.org/en/content/articlehtml/2021/na/d0na00678e [2021] |
2020
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1. Roy, S., Cha, J. N., & Goodwin, A. P. , "Nongenetic Bioconjugation Strategies for Modifying Cell Membranes and Membrane Proteins: A Review", Bioconjugate Chemistry, 31, 11, 2465-2475, https://pubs.acs.org/doi/full/10.1021/acs.bioconjchem.0c00529 [2020] |
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2. Harris, A. W., Harguindey, A., Patalano, R. E., Roy, S., Yehezkeli, O., Goodwin, A. P., & Cha, J. N., "Investigating Protein-Nanocrystal Interactions for Photodriven Activity", ACS Applied Bio Materials, 3, 2, 1026-1035, https://pubs.acs.org/doi/full/10.1021/acsabm.9b01025 [2020] |
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3. Roy, S., Brasino, M., Harguindey, A., Chapnick, D. A., Liu, X., Cha, J. N., Goodwin, A. P., "Enzymes Photo-Cross-Linked to Live Cell Receptors Retain Activity and EGFR Inhibition after Both Internalization and Recycling", Bioconjugate Chemistry, 31, 1, 104-112, https://pubs.acs.org/doi/full/10.1021/acs.bioconjchem.9b00781 [2020] |
2019
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1. Bull, D., Kienle D. F., Chaparro Sosa, A. F., Nelson, N., Roy, S., Cha, J. N., Schwartz D. K., Kaar, J. L., Goodwin, A. P., "Surface-templated nanobubbles protect proteins from surface-mediated denaturation", The journal of physical chemistry letters, 10, 11, 2641-2647, https://pubs.acs.org/doi/full/10.1021/acs.jpclett.9b00806 [2019] |
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2. Harguindey, A., Roy, S., Harris, A. W., Fairbanks B. D., Goodwin, A. P., Bowman, C. N., & Cha, J. N., "Click Nucleic Acid Mediated Loading of Prodrug Activating Enzymes in PEG-PLGA Nanoparticles for Combination Chemotherapy", Biomacromolecules, 20, 4, 1683-1690, https://pubs.acs.org/doi/full/10.1021/acs.biomac.9b00040 [2019] |
2018
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1. Brasino, M., Roy, S., Erbse, A. H., He, L., Mao, C., Park, W., Cha, J. N., Goodwin, A. P. , "Anti-EGFR Affibodies with Site-Specific Photo-Cross-Linker Incorporation Show Both Directed Target-Specific Photo- conjugation and Increased Retention in Tumors", Journal of the American Chemical Society (JACS), 140, 37, 11820-11828, https://pubs.acs.org/doi/full/10.1021/jacs.8b07601 [2018] |
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2. Yildirim, A., Shi, D., Roy, S., Blum, N. T., Chattaraj, R., Cha, J. N., & Goodwin, A. P., "Nanoparticle- Mediated Acoustic Cavitation Enables High Intensity Focused Ultrasound Ablation Without Tissue Heating. ", ACS Applied Materials and Interfaces, 10, 43, 36786-36795, https://pubs.acs.org/doi/full/10.1021/acsami.8b15368 [2018] |
2024
1. Roy, S. (Invited), "Use of therapeutic proteins against in vivo breast cancer tumor models.", International Conference on Frontiers in Nanomaterials Science: Aspects in Biotechnology and Chemical Engineering, NIT Patna [2024] |
2. Roy, S. (Invited), "Study of T cell migration on advanced in vitro tumor models.", CompFlu, IIT Hyderabad [2024] |
2023
1. Roy, S., Chen, Z., Crist, L., Zhang, H., Qian, G., Wood, D. K., Provenzano, P. P., "Development of T cell migration assays in advanced in vitro pancreatic tumor models", American Association of Cancer Research (AACR) Conference: Pancreatic cancer, Boston [2023] |
2. Roy, S., Chen, Z., Zhang, H., Qian, G., Provenzano, P., "Development of design criteria for T cell engineering for better transport through tumor stroma", National Cancer Institute (NCI) – Cellular Cancer Biology Imaging Research (CCBIR) Annual Investigators Meeting, University of Minnesota, Minneapolis [2023] |
3. Roy, S., Chen, Z., Provenzano, P., "T cell movement through complex obstacles presented by the tumor microenvironment", 8th Annual Midwest Tumor Micro-environemnt (TME) Meeting, Purdue University [2023] |
4. Roy, S. (Invited), "Migration of engineered T cells through the pancreatic spheroid stroma.", Centre for Multiparametric Imaging of Tumor Immune Microenvironment (C-MITIE) Retreat., University of Minnesota, Minneapolis [2023] |
2022
1. Roy, S., Curry, S. D., Cha, J. N., & Goodwin, A. P. , "Photocrosslinkable affibodies conjugated to upconverting nanoparticles used for in vivo prodrug therapy.", ACS National Fall Meeting, Chicago [2022] |
2021
1. Roy, S., Curry, S., Bibbey, M. G., Goodwin, A. P., & Cha, J. N. , "Induction of quiescence in breast cancer cells using photo-conjugating affibodies.", ACS National Spring Meeting, [2021] |
2019
1. Roy, S., Brasino, M., Harguindey, A., Cha, J. N., Goodwin, A. P., "Photo-conjugating affibodies to their receptors prevent their proteolytic degradation and preserves their activity.", ACS National Fall Meeting, San Diego [2019] |
