• Recent Publications
    73

    Stereoselective Synthesis of gem-Dihalopiperidines via Halo-Aza-Prins Cyclization Reaction: Access to Piperidin-4-ones and Pyridines| Surjya Kumar Bora, Subhamoy Biswas, Bipin Kumar Behera and Anil K. Saikia | Org. Biomol. Chem. 2024, DOI: 10.1039/D4OB00338A.

    72

    Synthesis of tetrahydroquinazolines from 2-aminobenzonitriles and alkylidene malonates via 1,4-conjugate addition and unprecedented rearrangement reaction| Bikoshita Porashar, Bipin Kumar Behera, Hunmoina Phukon and Anil K. Saikia | Chem. Commun. 2024, 60, 4358-4361.

    71

    Synthesis of Benzodioxepinones and Benzoxazepinones via Tandem Oxidation and Iodolactonization of 2-O/N-tethered Alkenyl Benzaldehyde Mediated by CuI/TBHP| Archana Chutia, Pallav Jyoti Arandhara, Bipin Kumar Behera, Ankita Pradhan and Anil K. Saikia | ACS Omega 2024, 9, 14217-14232.

    70

    Nitrile Stabilized Synthesis of Pyrrolidine and Piperidine Derivatives via Tandem Alkynyl aza-Prins-Ritter Reactions| Sudip Shit, Chinmayee Choudhury and Anil K. Saikia | Org. Biomol. Chem. 2024, 22, 568-578.

    69

    Leveraging cascade alkynyl Prins cyclization towards the stereoselective synthesis of spiro-furan quinazolinone scaffolds| Subhamoy Biswas, Sudip Shit, Bipin Kumar Behera, Archana Kumari Sahu and Anil K. Saikia | Chem. Commun. 2023, 59, 14301-14304.

    68

    Synthesis of 1,2,3-triazole-fused N-heterocycles from N-alkynyl hydroxyisoindolinones and sodium azide via Huisgen reaction| Pallav Jyoti Arandhara, Bipin Kumar Behera, Subhamoy Biswas and Anil K. Saikia | Org. Biomol. Chem. 2023, 21, 8772-8781.

    67

    Base-Promoted [4+2] Annulation Reaction of In Situ-Generated Azadienes from N-Propargylamines with Active Methylene Compounds: Access to Highly Functionalized 2-Pyridones| Bipin Kumar Behera, Pallav Jyoti Arandhara, Bikoshita Porashar, Surjya Kumar Bora and Anil K. Saikia | J. Org. Chem. 2023, 88, 15041–15059.

    66

    Regio- and Chemoselective Synthesis of 3-(Dihydrofuran-3(2H)-ylidene)isobenzofuran-1(3H)-imines via Tandem Alkynyl Prins- and Intramolecular Oxycyclization Reactions| Sudip Shit, Bipin Kumar Behera, Subhamoy Biswas and Anil K. Saikia | J. Org. Chem. 2023, 88, 10844–10857.

    65

    Review of electrochemical transition-metal-catalyzed C−H functionalization reactions| Sumi Changmai, Sabera Sultana and Anil K. Saikia | ChemistrySelect 2023, 8, e202203530.

    64

    Synthesis of Heterocyclic Scaffolds via Prins, Oxonium-Ene and Related Cyclization Reactions| Anil K. Saikia | Synlett 2023; 34, 507-534.(On invitation to publish in a "Chemical Synthesis and Catalysis in India" SYNLETT Special Issue)

    63

    Diastereoselective Synthesis of 2,6-Disubstituted Tetrahydropyranones via Prins Cyclization of 3-Bromobut-3-en-1-ols and Aldehydes| Surjya Kumar Bora, Sudip Shit, Archana Kumari Sahu and Anil K. Saikia | J. Org. Chem. 2023, 88, 3012-3021.

    62

    Temperature Tunable Synthesis of Tetrahydro-4H-pyrrolo[3,2-c]quinolin-4-ones and Dihydro-1H-benzo[b]azepines from 2-Aminobenzonitriles and Donor–Acceptor Cyclopropanes| Bikoshita Porashar, Subhamoy Biswas, Archana Kumari Sahu, Archana Chutia and Anil K. Saikia | Org. Lett. 2022, 24, 9038-9042.

    61

    Synthesis of Spiro[furan-2,1′-isoindolin]-3′-ones from 2-(4-Hydroxybut-1-yn-1-yl)benzonitriles and Aryl Aldehydes under the Action of Triflic Acid| Sudip Shit, Surjya Kumar Bora, Archana Kumari Sahu and Anil K. Saikia | J. Org. Chem. 2022, 87, 11634-11643.

    60

    Synthesis of Thiazole-2(3H)-ones via [3,3]-Sigmatropic Rearrangement/5-exo-dig Cyclization of N-Propargylamines| Bipin Kumar Behera, Sudip Shit, Subhamoy Biswas and Anil K. Saikia | J. Org. Chem. 2022, 87, 9259-9269.

    59

    Synthesis of 3C-alkylated active methylene substituted 2H-indazole derivatives via sequential ring opening of donor acceptor cyclopropanes and reductive cyclization reaction| Archana Kumari Sahu, Subhamoy Biswas, Surjya Kumar Bora and Anil K. Saikia | New J. Chem. 2022, 46, 12456-12460.

    58

    Synthesis of pyrimido[2,1-a]isoindolone and isoindolo[2,1-a]quinazolinone via intramolecular aza-Prins type reaction| Subhamoy Biswas, Bikoshita Porashar, Pallav Jyoti Arandhara and Anil K. Saikia | Chem. Commun. 2021, 57, 11701-11704.

    57

    K2S2O8-Mediated Synthesis of Highly Functionalized Pyrroles via Oxidative Self-Dimerization of N-Propargylamines| Bipin Kumar Behera, Archana Kumari Sahu, Ngangbam Renubala Devi and Anil K. Saikia | J. Org. Chem. 2021, 86, 12481-12493.

    56

    Synthesis of dibenzocyclohepta[1,2-a]naphthalene derivatives from phenylacetaldehyde and alkynyl benzyl alcohols via sequential electrophilic addition and double Friedel-Crafts reactions| Archana K. Sahu , Ramanjaneyulu Unnava, Bipin K. Behera and Anil K. Saikia | Org. Biomol. Chem. 2021, 19, 2430-2435.

    55

    Synthesis of 4-Vinyl-1,2,3,4-tetrahydroisoquinoline from N-Tethered Benzyl-Alkenol Catalyzed by Indium(III) Chloride: Formal Synthesis of (+/-)-Isocyclocelabenzine| Ngangbam Renubala Devi, Sudip Shit, Bipin Kumar Behera and Anil K. Saikia | Synthesis 2020, 52, 1425-1434. (This article is published as a Virtual Thematic Collection of top 20 cited articles published from India in year 2020 and 2021 by Synthesis, DOI: 10.155/s-00000084)

    54

    In(OTf)3-Catalyzed One-Pot Tandem Mannich and Conia-Ene Cyclization Reaction of N-Propargyl Amido Alcohols with 1,3-Dicarbonyl Compounds: An Approach To Construct Tetrahydro-1H-pyrrolo[2,1-a]isoindolone-1,1-dicarboxylate and Its Application| Archana K. Sahu , Ramanjaneyulu Unnava, Sudip Shit and Anil K. Saikia | J. Org. Chem. 2020, 85, 1961-1971.

    53

    Bismuth(III)-Triflate-Catalyzed Highly Diastereoselective Synthesis of Substituted Tetrahydrothiophene via Tandem Isomerization, Michael and Aldol Reactions| Upasana Borthakur and Anil K. Saikia | ChemistrySelect 2019, 4, 11136-11139.

    52

    Vinylsilanes in Highly Diastereo- and Regio-Selective Synthesis of Dihydropyrans| Upasana Borthakur, Subhamoy Biswas and Anil K. Saikia | ACS Omega 2019, 4, 2630-2636.

    51

    Stereoselective synthesis of hexahydrofuro[3,4-b]furan-4-ol and its dimer via tandem Prins and pinacol rearrangement| Sudip Shit, Namita Devi, Ngangbam Renubala Devi and Anil K. Saikia | Org. Biomol. Chem. 2019, 17, 7398-7407.

    50

    Stereoselective Synthesis of 4-O-Tosyltetrahydropyrans via Prins Cyclization Reaction of Enol Ethers| Sujit Sarkar, Namita Devi, Bikoshita Porashar, Santu Ruidas and Anil K Saikia | SynOpen 2019, 03, 36-45.

    49

    Regio- and Diastereoselective Synthesis of Dihydropyrans and Pyranopyrans via Oxonium-Ene Reaction of beta-Allenols and Aldehydes| Ngangbam Renubala Devi, Sabera Sultana, Madhurjya Borah and Anil K. Saikia | J. Org. Chem. 2018, 83, 14987-14998.

    48

    Stereoselective Synthesis of Pyrroloisoindolone and Pyridoisoindolone via aza-Prins Cyclization of Endocyclic N-Acyliminium Ions| Malay Das and Anil K. Saikia | J. Org. Chem. 2018, 83, 6178-6185.

    47

    Ene Cyclization Reaction in Heterocycle Synthesis | Pipas Saha and Anil K. Saikia | Org. Biomol. Chem. 2018, 16, 2820-2840.

    46

    FeCl3-Mediated Carbenium Ion-Induced Intramolecular Cyclization of N-Tethered Alkyne-Benzyl Alkanols| Madhurjya Borah and Anil K. Saikia | ChemistrySelect 2018, 3, 2162-2166.

    45

    Synthesis of Methyl 4-(7-hydroxy-4,4,8-trimethyl-3-oxabicyclo[3.3.1]nonan-2-yl)benzoate and their evaluation as anti-leishmanial: Synergistic effect with Miltefosine| Prachi Bhalla, Sabera Sultana, Adarsh Kumar Chiranjivi, Anil K Saikia and Vikash Kumar Dubey | Antimicrob. Agents Chemother. 2018, 62, e01810-17.

    44

    Stereo- and Regioselective Synthesis of 4-Vinylpyrrolidine from N-Tethered Alkyne-Alkenol| Ngangbam Renubala Devi, Bipin k Behera and Anil K. Saikia | ACS Omega. 2018, 3, 576.

    43

    Intramolecular Pictet-Spengler Reaction of Cyclic Iminium ions: A Novel Access to Benzo[1,4] oxazepine Fused Tetrahydroisoquinoline and Tetrahydro-beta-carboline Analogues| Ramanjaneyulu Unnava, Archana Kumari Sahu and Anil K. Saikia | Asian J. Org. Chem. 2017, 6, 1003-1007.

    42

    Diastereoselective Synthesis of Substituted Morpholines from N-Tethered Alkenols: Total Synthesis of Chelonin A | Madhurjya Borah; Upasana Borthakur; Anil K. Saikia | J. Org. Chem. 2017, 82, 1330.

    41

    Synthesis of dihydroindenol[1,2-c]isochromene via cascade cyclization and Friedel-Crafts reaction | Priya Ghosh; Manash J Deka; Madhurjya Borah; Anil K. Saikia | RSC. Adv. 2016, 6, 106656.

    40

    Highly regioselective synthesis of 4-tosylthiomorpholine via intramolecular cyclization of N-tethered thioalkenols | Manash J Deka; Upasana Borthakur; Anil K. Saikia | Org. Biomol. Chem. 2016, 14, 10489.

    39

    Synthesis of Tetrahydro-1H-indeno[1,2-b]pyridine via Cascade Cyclization and Friedel-Crafts Reaction | Upasana Borthakur; Madhurjya Borah; Manash J Deka; Anil K. Saikia | J. Org. Chem. 2016, 81, 8736.

    38

    Synthesis of Highly Substituted 4-Iodopyrazole N-oxides and Pyrazoles from Propargylamines | Ramanjaneyulu Unnava; Manash J Deka; Anil K. Saikia | Asian J. Org. Chem. 2016, 5, 528.

    37

    Synthesis of Substituted Pyrazole N-Oxide and Pyrazole from Propargyl Amine | Ramanjaneyulu Unnava; Anil K. Saikia | ChemistrySelect. 2016, 1, 1816.

    36

    Synthesis of Isochroman Derivatives via Oxa-Pictet-Spengler Reaction of Vinylogous Esters | Sujit Sarkar; Sabera Sultana; Kiran Indukuri; Ramanjaneyulu Unnava; Anil K. Saikia | Synthesis. 2016, 48, 1727.

    35

    Lewis acid mediated intramolecular C-O bond formation of alkanol-epoxide leading to substituted morpholine and 1,4-oxazepane derivatives: Total synthesis of(+)-viloxazine | Priya Ghosh; Manash J Deka; Anil K. Saikia | Tetrahedron. 2016, 72, 690.

    34

    Synthesis of 4-trifluoromethanesulfonate substituted 3,6-dihydropyrans and their application in various C-C coupling reactions | Priya Ghosh; Ashutosh Kr. Kautarya; Anil K. Saikia | RSC. Adv. 2016, 6, 44774.

    33

    Diastereoselective synthesis of substituted hexahydrobenzo[de]isochromanes and evaluation of their antileishmanial activity | Anil K. Saikia; Sabera Sultana; Ngangbam Renubala Devi; Manash J Deka; Kartikeya Tiwari; Vikash K. Dubey | Org. Biomol. Chem. 2016, 14, 970.

    32

    Novel leads against Miltefosine unresponsive Leishmania donovani | Mousumi Das; Gundappa Saha; Sabera Sultana; Anil K. Saikia; Vikash K. Dubey | Antimicrob Agents Chemother. 2015, 59, 7826.

    31

    Synthesis of Substituted Tetrahydropyrans and Tetrahydrofurans via Intramolecular Hydroalkoxylation of Alkenols | Sabera Sultana; Ngangbam Renubala Devi; Anil K. Saikia | Asian J. Org. Chem. 2015, 11, 1281.

    30

    Synthesis of Five-, Six-, and Seven-Membered 1,3- and 1,4-Heterocyclic Compounds via Intramolecular Hydroalkoxylation/Hydrothioalkoxylation of Alkenols/Thioalkenols | Manash J Deka; Kiran Indukuri; Sabera Sultana; Madhurjya Borah; Anil K. Saikia | J. Org. Chem. 2015, 80, 4349.

    29

    Diastereoselective Synthesis of Substituted Tetrahydrothiophenes and thiopyrans via Thia-Prins Cyclization Reaction | Madhurjya Borah; Paramartha Gogoi; Kiran Indukuri; Anil K. Saikia | J. Org. Chem. 2015, 80, 2641.

    28

    Regioselective One-pot, Three-component Synthesis of Substituted 2H-Indazoles from Nitroarylaldehyde, Alkyne and Amine Catalyzed by CuBr/Zn(OTf)2 System | Anil K. Saikia; Ramanjaneyulu Unava; Kiran Indukuri; Sujit Sarkar | RSC Adv. 2014, 4, 55296.

    27

    Diastereoselective Synthesis of Substituted Tetrahydrofurans via Prins Cyclization of Enol Ethers | Paramartha Gogoi; Vijay Kumar Das; Anil K. Saikia | J. Org. Chem. 2014, 79, 8592.

    26

    In Vivo Assessment of Antileishmanial Property of 4-(4,4,8-Trimethyl-7- oxo-3-oxabicyclo[3.3.1]non-2-yl)-benzoic Acid Methyl Ester, an Oxabicyclo[ 3.3.1]nonanones | Prakash Saudagar; Shyam Lal Mudavath; Pipas Saha; Anil K. Saikia; Shyam Sundar; Vikash Kumar Dubey | Letters in Drug Design & Discovery. 2014, 11, 937.

    25

    Stereoselective synthesis of O-tosyl azabicyclic derivatives via aza Prins reaction of endocyclic N-acyliminium ions: application to the total synthesis of (+/-)-epi-indolizidine 167B and 209D | Anil K. Saikia; Kiran Indukuri; Jagadish Das | Org. Biomol. Chem 2014, 12, 7026.

    24

    Lewis Acid Mediated Intramolecular C-C bond formation of Alkyne-Epoxide Leading to Six Membered Nitrogen and Oxygen Heterocycles | Priya Ghosh; Pipas Saha; Somasekhar Bondalapati; Kiran Indukuri; Anil K. Saikia | J. Org. Chem. 2014, 79, 4119.

    23

    Diastereoselective Synthesis of Dihydropyrans via Prins Cyclization of Enol Ethers: Total Asymmetric Synthesis of (+)-Civet Cat Compound | Sabera Sultana; Kiran Indukuri; Manash J Deka; Anil K. Saikia | J. Org. Chem. 2013, 78, 12182.

    22

    Stereoselective Synthesis of Amido and Phenyl Azabicyclic Derivatives via a Tandem Aza Prins-Ritter/Friedel-Crafts Type Reaction of Endocyclic N-Acyliminium Ions | Kiran Indukuri; R.Unnava; Manash J Deka; Anil K. Saikia | J. Org. Chem. 2013, 78, 10629.

    21

    Molecular mechanism underlying antileishmanial effect of oxabicyclo[3.3.1]nonanones: Inhibition of key redox enzymes of the pathogen | Prakash Saudagar; Pipas Saha; Anil K. Saikia; Vikash Kumar Dubey | Eur. J. Pharm. Biopharm. 2013, 85, 569.

    20

    Unveiling the mode of action of antibacterial labdane diterpenes from Alpinia nigra (Gaertn.) B. L. Burtt seeds | Sudipta Ghosh; Kiran Indukuri; Somasekhar Bondalapati; Anil K. Saikia; Latha Rangan | Eur. J. Med. Chem. 2013, 66, 101.

    19

    An Efficient Method for the Synthesis of 10-Aminoartemisinin Derivative | Pipas Saha; Anil K. Saikia | J. Heterocyclic Chem. 2013, 50, 207.

    18

    Scandium(III) triflate catalyzed synthesis of primary homoallylic alcohols via carbonyl-ene reaction | Sabera Sultana; Somasekhar Bondalapati; Kiran Indukuri; Paramartha Gogoi; Pipas Saha; Anil K. Saikia | Tetrahedron Lett. 2013, 54, 1576.

    17

    Stereoselective Synthesis of Tetrahydroquinolines Through an Imino-Ene Cyclization Reaction | Somasekhar Bondalapati; Kiran Indukuri; Priya Ghosh; Anil K. Saikia | Eur. J. Org. Chem. 2013, 952.

    16

    Diastereoselective synthesis of substituted dihydropyrans via an oxonium-ene cyclization reaction | Pipas Saha; Priya Ghosh; Sabera Sultana; Anil K. Saikia | Org. Biomol. Chem. 2012, 10, 8730.

    15

    Synthesis of 2,3-dihydro-4-pyranones from epoxides via intermolecular [4+2]cycloaddition reaction | Kiran Indukuri; Somasekhar Bondalapati; Sabera Sultana; Anil Kumar Saikia | RSC Adv. 2012, 2, 9398.

    14

    Application of a novel 1,3-diol with a benzyl backbone as chiral ligand for asymmetric oxidation of sulfides to sulfoxides | Paramartha Gogoi; Trimurthulu Kotipalli; Kiran Indukuri; Somasekhar Bondalapati; Pipas Saha; Anil K. Saikia | Tetrahedron Lett. 2012, 53, 2726.

    13

    Stereoselective, one-pot, three-component synthesis of 4-aryltetrahydropyrans from epoxides via prins cyclization reaction | Kiran Indukuri; Somasekhar Bondalapati; Trimurtulu Kotipalli; Paramartha Gogoi; Anil K. Saikia | Synlett 2012, 233.

    12

    Synthesis of 2,3,5,6-tetrasubstituted tetrahydropyrans via (3,5)-oxonium-ene reaction | Pipas Saha; Anup Bhunia; Anil K. Saikia | Org. Biomol. Chem. 2012, 10, 2470.

    11

    Stereoselective synthesis of 6-oxabicyclo[3.2.1]octene via (3,5)-oxonium-ene reaction | Pipas Saha; Anil K. Saikia | Tetrahedron 2012, 68, 2261.

    10

    Diastereoselective Synthesis of Substituted Tetrahydrothiopyrans via (3,5)-Thionium-Ene Cyclization Reaction | Somasekhar Bondalapati; Paramartha Gogoi; Kiran Indukuri; Anil K. Saikia | J. Org. Chem. 2012, 77, 2508.

    09

    Axial-selectivity in Prins cyclization reaction. Synthesis of 4-iodotetrahydropyrans | Anil K Saikia; Somasekhar Bondalapati; Kiran Indukuri; Paramartha Gogoi | Chem. Lett. 2011, 40, 1176.

    08

    Synthesis of oxabicyclo[3.3.1]nonenes and substituted tetrahydropyrans via (3,5)-oxonium-ene reaction | Pipas Saha; Paramartha Gogoi; Anil K. Saikia | Org. Biomol. Chem. 2011, 9, 4626.

    07

    An efficient synthesis of dihydro- and tetrahydropyrans via oxonium-ene cyclization reaction | Somasekhar Bondalapati; Udagandla C. Reddy; Pipas Saha; Anil K. Saikia | Org. Biomol. Chem. 2011, 9, 3428.

    06

    One-pot, three-component synthesis of 4-aryl-5,6-dihydropyran via prins-friedel-crafts reaction | Udagandla C. Reddy; Anil K. Saikia | Synlett 2010, 1027.

    05

    A Novel Synthesis of Oxabicyclo [3.3.1] nonanone via (3,5)-Oxonium-Ene Reaction | Pipas Saha; U. C. Reddy; Somasekhar Bondalapati; Anil K. Saikia | Org. Lett. 2010, 12, 1824.

    04

    Titanium tetrafluoride: An efficient Lewis acid and fluorinating agent for stereoselective synthesis of 4- fluorotetrahydropyran | Somasekhar Bondalapati; U. C. Reddy; D. S. Kundu; Anil K. Saikia | J. Fluo. Chem. 2010, 131, 320.

    03

    Cerium (IV) triflate-catalyzed selective oxidation of sulfides to sulfoxides with aqueous hydrogen peroxide | B. Rama Raju; S. Sarkar; U. Chandramoulali Reddy; Anil K. Saikia | J. Mol. Catl. A: Chem. 2009, 308, 169.

    02

    Stereoselective synthesis of 2,6-disubstituted-4-aryltetrahydropyrans using Sakurai-Hosomi-Prins-Friedel-Crafts reaction | Udagandla C. Reddy; Somasekhar Bondalapati; Anil K. Saikia | Eur. J. Org. Chem. 2009, 1625.

    01

    Stereoselective One-Pot, Three-Component Synthesis of 4-Aryltetrahydropyran via Prins-Friedel-Crafts Reaction | U. C. Reddy; Somasekhar Bondalapati; Anil K. Saikia | J. Org. Chem. 2009, 74, 2605.

© Department of Chemistry, Indian Institute of Technology Guwahati