Module B: Neural Engineering and Neuromodulation December 9-13, 2019
Day 6
Date: 9/12/2019
Monday
Overview of Neuro-Devices & Neuroprosthetic Interfaces
(DKC)
Lecture 11: 9:30 to 10:30 AM
Introduction to neural engineering, brain-machine interfaces, and neuromodulatory devices, including historical perspectives and conventional applications in treating nervous system disorders.
Lecture 12: 10:45 to 11:45 AM
Discussion of emerging strategies, technologies, and trends in neuroprosthetic interface, nervous system modulation, and bio-hybrid microsystems.
Lecture 13: 3:00 to 4:00 PM
Neuromodulation strategies in the CNS and PNS, including design concepts, mechanisms of action, and clinical/experimental devices; focus on next-generation optogenetics-based and tissue engineered “living electrodes” for biologically-based neuromodulation.
Day 7
Date: 10/12/2019
Tuesday
Tutorial 2 Tutorial 2: 11:00 AM to 1:00 PM.
Hand out the second assignment.
Day 8
Date: 11/12/2019
Wednesday
Bio-Hybrid Microsystems as Neurofidelic Testbeds In vitro
(DKC)
Lecture 14: 10:00 to 11:00 AM
Brain-machine interface and peripheral interface strategies, including design concepts, mechanisms of action, and clinical/experimental devices; focus on next-generation bio- hybrid neural-electrical-optical interfaces.
Lecture 15: 11:15 AM to 12:15 PM
Principles of constructing self-contained bio-hybrid microsystems in vitro, including cell/tissue engineering considerations, micro-electrical-mechanical systems fabrication, micro-fluidic activity, optical activation and reporting, and real-time dynamic measurements/feedback
Lecture 16: 3:00 to 4:00 PM
Applications of bio-hybrid microsystems as in vitro investigational platforms for modeling disease/regenerative mechanisms, pharmacologic screening, “brain-on-a-chip”, and pre- animal testing of tissue engineered constructs
Day 9
Date: 12/12/2019
Thursday
Technology Landscape in Neural Engineering and Tissue Engineering
(DKC+UB)
Lecture 17: 9:30 to 10:30 AM
Present technology, intellectual property, and commercial landscape for clinically available devices, artificial conduits, and tissue engineered organs/constructs (DKC)
Lecture 18: 10:45 to 11:45 AM
Potential current and future use of neural engineering and tissue engineering technology in the Indian clinical system for nervous system repair and functional restoration (UB)
Day 10
Date: 13/12/2019
Friday
Discussion: Course Summary and Future Directions
(DKC+UB)
Lecture 19: 9:30 to 10:30 AM
Review of emerging trends in tissue and neural engineering; discussion of major barriers/challenges to clinical implantation; highlight the role of engineers in ushering in the coming era of restorative neurology and neurosurgery (DKC)
Lecture 20: 10:45 to 11:45 AM
Overall course summary and feedback of Module B (DKC+UB)
Submission of second assignment
Discussion and final examination: 2:00 to 4:00 PM