EMT LAB

Welcome to the “Enzyme and Microbial Technology Research Group”. Microbes have been one of the most primitive yet successful living forms. They have been successful in outnumbering all other living forms and maintaining their success in various ways by effecting all higher life forms. “Respected for their boon and feared for the banes”. The EMT research group studies microbes for their features of boon and bane in different spectrums of “Metagenomics, Industrial Microbiology, Extremophiles, Environmental Biotechnology, Disease Therapeutics and diagnosis”.

The group also focuses on Proteins – the work horse of life forms. Proteins - a string of amino acids doing wonders!!!! Nature designs everything with a purpose. Proteins also fall into this regime of nature. The research group efforts to understand the unwritten constitutional laws of nature framed for proteins. The uniqueness in sequence and structure of proteins renders them specific function. The obedients and the extremists!!!! Some enzymes as endonuclease, RNA polymerase and nitrite reductase from Pyrococcus furiosus are active at extreme temperature close to 100 degree centigrade, while others as lipases from Candida antarctica perform best at sinking mercury levels. Pseudomonas aeruginosa lipase is functional in organic solvents as n-decane, ethyleneglycol, Dimethylsulphoxide, n-octane, n-heptane, isooctane, and cyclohexane carrying out transesterification and racemization reactions. Alakliphiles as Spirulina maxima and acidophiles as Alicyclobacillus acidocaldarius are not bothered by extremes of pH. The research group tries to intrude into these aspects of proteins, trying to find what can be done to emulate their function, lengthen their in vivo storage, deliver them at required destinations exploiting them as biomarkers for diagnosis, inhibiting them for therapeutics etc.