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Research Areas |
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Study of cancer microenvironment in
chemoresistance
The life of cancer patients have been extended by many
therapeutic molecules and methods developed in the recent past. However, cancer
chemo-resistance is also a growing problem and a cause for great
concern in securing the lives of cancer patients. Our group
focuses on the mechanisms of cancer chemo-resistance - oncogene
dependent/independent pathways and most importantly the
microenvironment mediated chemo-resistance.
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Signaling
pathways during cancer metastasis
Migration of cancer
cells through the tissue into the bloodstream is an important
step during metastasis. We are studying the
signaling pathways that are activated during this process.
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Understanding mesenchymal
stem cell biology
Tissue damage occurs during
aging, injury or infection. The regenerative and repair
potential of tissues and organs in the human body are varied and
limited and there is a great need for therapeutic approaches
that result in efficient tissue repair and regeneration. Stem
cells are a great source of cells for such applications and they can be modified genetically or
tweaked by application of small molecules or extra cellular
matrix substances.
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Funded by:
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Department of Biotechnology (DBT)
Science and Engineering Research Board (SERB)
Indian Council of Medical Research (ICMR)
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Collaborators
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1. Hematology, Gauhati Medical College Hospital, Guwahati, India
2. Sri Sankaradeva Nethralaya Hospital, Guwahati, India
3. Assam Medical College Hospital, Dibrugarh, India
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