Indian Institute of Technology Guwahati
Department of Biosciences and Bioengineering

Stem Cell and Cancer Biology Group



Study of cancer microenvironment  in chemoresistance

The life of cancer patients have been extended by many therapeutic molecules and methods developed in the recent past. However, cancer chemo-resistance is also a growing problem and a cause for great concern in securing the lives of cancer patients. Our group focuses on the mechanisms of cancer chemo-resistance - oncogene dependent/independent pathways and most importantly the microenvironment mediated chemo-resistance.


Kumar et al, 2017a; Kumar et al, 2017b]

Understanding mesenchymal stem cell biology

Tissue damage occurs during aging, injury or infection. The regenerative and repair potential of tissues and organs in the human body are varied and limited and there is a great need for therapeutic approaches that result in efficient tissue repair and regeneration. Stem cells are a great source of cells for such applications and they can be modified genetically or tweaked by application of small molecules or extra cellular matrix substances.


Signaling pathways during cancer metastasis

Migration of cancer cells through the tissue into the bloodstream is an important step during metastasis. We are studying the signaling pathways that are activated during this process.

Research facilities

Our lab is well-equipped for our research work and facilities are regularly added to increase the scope of the work we do.

Funded by:

Department of Biotechnology (DBT)
Science and Engineering Research Board (SERB)
Indian Council of Medical Research (ICMR)


1. Hematology, Gauhati Medical College Hospital, Guwahati, India
2. Sri Sankaradeva Nethralaya Hospital, Guwahati, India
3. Assam Medical College Hospital, Dibrugarh, India

Last updated: Aug 2017