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Publications and Patents

Total Number of Citation : 884; H-Index : 14 ; I10 Index=18 (based on google scholar)
(a) Cumulative Impact factor: 210.18
(b) As first or corresponding author: 155.41


  1. Trivedi, V., Gupta, A., Rao, J.V.K., Saravanan, P., Rao, G.S.J., Rao, A.N., Savithri, H.S. and Subramanya, H.S. (2002) Crystal Structure of Binary and Ternary Complexes of Serine Hydroxymethyl-transferase from B.Stearothermophilus: Insights into the Catalytic Mechanism.J. Biol. Chem. 277, 17161-17169. [Impact Factor= 4.651] [Publisher: American Society of Biochemistry and Molecular Biology].

  2. Sarkhel, S., Sharon, A., Trivedi, V., Maulik, P. R., Singh, M. M., Venugopalan, P., Ray, S. (2003) Structure-Based Drug Design : Synthesis, Crystal Structure, Biological Evalution and Docking Studies of Mono- and Bis-Benzo[b] Oxepines as Non-steroidal estrogens.Bioorg.Med.Chem.11, 5025-5033. [Impact Factor= 2.338] [Publisher: Elsevier].

  3. Bhavani S., Trivedi V., Ambili M., Jala V.R., Subramanya H.S., Purnima K., Appaj R.N., Savithri, H.S. (2005) Role of Lys-226 in the Catalytic Mechanism of Bacillus Stearothermophilus Serine Hydroxymethyl-transferase – Crystal Structure  and Kinetic Studies. Biochemistry, 44 (18), 6929 -6937. [Impact Factor= 3.377]  [Publisher: American Chemical Society].

  4. Trivedi, V ., Srivastava, K., Puri, S.K., Maulik, P.R ., Bandyopadhyay, U (2005) Purification and Biochemical Characterization of a Heme Containing Peroxidase from the Human Parasite P. falciparum. Protein  Expr Purif. 37 (2) ; 154-161. [Impact Factor= 1.429]  [Publisher: Elsevier].

  5. Trivedi, V., Chand, P., Maulik, P. R., Bandyopadhyay, U. (2005) Mechanism of Horseradish Peroxidase - Catalyzed Heme Oxidation and Polymerization (β--Hematin formation).Biochem. Biophys. Acta. 1723, 221-228. [Impact Factor= 3.848]  [Publisher: Elsevier].

  6. Trivedi, V., Chand, P., Srivastava, K., Puri, S. K., Maulik, P. R., Bandyopadhyay, U.(2005) Clotrimazole Inhibits Hemo- Peroxidase of P. falciparum and Induces Oxidative Stress : Proposed Antimalarial Mechanism of Clotrimazole.  J. Biol. Chem. 280, 41129-41136. [Impact Factor= 4.651] [Publisher: American Society of Biochemistry and Molecular Biology].

  7. Stockinger W, Zhang, S.C., Trivedi, V, Jarzylo, L. A., Shieh, E. C., Lane, W.S., Castoreno, A. B. and Nohturfft,A (2006)Differential Requirements for Actin Polymerization, Calmodulin and  Ca2+ Define Distinct Stages of Lysosome/Phagosome Targeting. Mol. Biol. Cell, 17 : 1697-1710. [Impact Factor= 5.98] [Publisher: American Society for cell biology].

  8. Trivedi, V.,Zhang, S.C., Castoreno, A.B.,  Stockinger W, Shieh, E.C., Vyas, J.M., Frickel, E and Nohturfft, A. (2006) Immunoglobin G Signaling Activates Phagosome/Lysosome Targeting. Proc Natl Acad Sci U S A. ;103(48):18226-31. [Impact Factor= 9.737] [Publisher: Proceeding of the National Academy of Sciences of the United states of America]. This article was selected as “Science Editor Choice article” ( Science (2006), 314, 5806 : 1661) and featured in ASBMB Today.

  9. Trivedi, V, Zhang, SC,  Stockinger, W  and Nohturfft, A (2007). A Cell-Free Scintillation Proximity Assay for Studies on Lysosome-to-Phagosome Targeting. Science STKE,  Vol 2007, Issue 392, pl3.             [Impact Factor= 4.651] [Publisher: Science Press]. Featured on Faculty of 1000 biology.

  10. Ahmad, R., Raina, D., Trivedi, V., Ren, J., Rajabi, H., Kharbanda, S., Kufe, D. (2007) MUC1 Oncoprotein activates the IkB kinase β Complex and Constitute NF-κB Signaling. Nature Cell Biology, 9: 1419-1427 (2007). [Impact Factor= 20.76] [Publisher: Nature Publishing group]. This Article appear as “Featured articles: Cancer Signaling: MUC1 mucks up Apoptosis” in Nature Signaling Updates. 

  11. Trivedi, V, Adrienne Boire, Boris Tchernychev, Nicole Kaneider, Andrew J Ledger, Katie O’ Callaghan, Lidija Covic & Athan Kuliopulos (2009) Platelet Matrix Metalloprotease-1 Mediates Thrombogenesis By Activating PAR1 At A Novel Cryptic Ligand Site. Cell, 137 (2), 332-43. [Impact Factor= 31.95] [Publisher: Cell Press].

  12. Swift, S., Xu, J., Trivedi, V., Austin, KM., Tressel, SL., Zhang, L., Covic, L., Kuliopulos, A (2010) A novel PAR1-Interactor, Bicaudal-D1, regulates G protein signaling and internalization. Identification of the microtubule associated protein, Bicaudal-D1, as a novel regulator of PAR1-G Protein Signaling. J. Biol. Chem, Feb, 17, 2010 (Epub ahead of Print). [Impact Factor= 4.651] [Publisher: American Society of Biochemistry and Molecular Biology].

  13. Balaji, SN and Trivedi, V* (2012). Extracellular Methemoglobin mediated early ROS spike triggers osmotic fragility and RBC destruction: An Insight into the enhanced hemolysis during malaria. Ind J Clin Biochem, 27 (2): 178-185 [Corresponding Author]. [Publisher: Springer].  

  14. Trivedi, V* and Nag, S (2012) In Silico Characterization of Atypical Kinase, PFD0975w from plasmodium kinome: A suitable target for drug discovery. Chem Biol Drug Des. 2012 Apr;79(4):600-9. [Corresponding Author] [Impact Factor= 2.46]. [Publisher: Wiley Press].

  15. Prasad, KMN and Trivedi, V* (2012) Engineering High Resolution Horizontal Native PAGE for Proteins. International Research Journal of Biotechnology, Vol 3(4) pp 40-46. [Corresponding Author]

  16.  Nag, S., Prasad, KMN and Trivedi, V* (2012) Identification and screening of antimalarial Phytochemical reservoir from northeastern Indian plants to develop PfRIO-2 Kinase Inhibitor. Eur Food Res Technol, 234: 905-911. [Corresponding Author]. [Impact Factor= 1.43] [Publisher: Springer].

  17. Nag, S., Prasad, KMN., Bhowmick, A., Deshmukh, R., Trivedi, V* (2013) PfRIO-2 Kinase is a potential therapeutic target of antimalarial protein kinase inhibitors. Curr Drug Discov Technol, 10, 85-91. [Corresponding Author]. [Cites Per Doc= 3.0] [Publisher: Bentham Science Publisher].

  18. Deshmukh, R., Trivedi, V* (2013)  Methemoglobin exposure produces toxicological effects in macrophages due to multiple ROS spike induced apoptosis. Toxicology in    Vitro, 27: 16-23. [Corresponding Author] [Impact Factor= 2.650] [Publisher: Elsevier].

  19. Dwivedi, A., Prasad, KMN., Trivedi, V., Iyer, P (2012) Interaction of Heme Proteins with Anionic Polyfluorene: In-sights into Physiological Effects, Folding Events and Inhibition Activity. Appl. Mater. Interfaces, 4 (11), 6371–6377. [Impact Factor= 5.008] [Publisher: American Chemical Society Publications].

  20. Balaji, SN and Trivedi, V* (2013) Extracellular Methemoglobin Primes Red Blood Cell Aggregation in Malaria: An In-Vitro Mechanistic Study. FEBS Letters, 587, 350-357. [Corresponding Author] [Impact Factor= 3.58] [Publisher: Elsevier]

  21. Balaji, SN and Trivedi, V* (2013) Methemoglobin incites the primaquine toxicity through single electron oxidation and modification. J Basic Clin Physiol Pharmacol; 24(2): 105–114. [Corresponding Author] [Publisher: De Gruyter].

  22. Balaji, SN and Trivedi, V* (2013) Mechanism based suicidal inactivation of methemoglobin protects oxidative stress induced RBC lysis: Role of thiyl radicals of NAC in antioxidant potentials. Current Molecular Medicine, 13 (6), 1000-1009. [Corresponding Author] [Impact Factor= 4.6] [Publisher: Bentham Science Publisher].

  23. Deshmukh, R and Trivedi, V* (2013) Pro-stimulatory role of methemoglobin in inflammation through Hemin Oxidation and Polymerization. Inflamm Allergy Drug Targets, 12 (1), 68-78. [Corresponding Author] [Cites Per Doc= 2.6] [Publisher: Bentham Science Publisher].

  24. Nag, S., Chouhan, DK., Balaji, SN., Chakraborty, A., Lhouvum, K., Bal, C., Sharon, A and Trivedi, V* (2013) Comprehensive screening of heterocyclic compound libraries to identify novel inhibitors for PfRIO-2 kinase through docking and substrate competition studies. Med Chem Res, 22; 4737-4744. [Corresponding Author] [Impact Factor= 1.6] [Publisher: Springer].

  25. Lhouvum, K., Ramakrishnan, V and Trivedi, V* (2013) Insight into structural and Biochemical determinants of substrate specificity of PFI1625c: Correlation analysis of protein-peptide molecular models. J of molecular graphics and modeling, 43, 21-30. [Corresponding Author] [Impact Factor= 2.3] [Publisher: Elsevier]

  26. Manu S, Rohitas Deshmukh, KMN Prasad and Trivedi, V* (2013) Screening and Characterization of Antimalarial Heme Polymerase Inhibitors From Dietary Garlic Cloves. European journal of medicinal plants, 3(3) 474-484. [Corresponding Author]. [Publisher: Science Domain International].

  27. Jain, A., Trivedi, V* (2013) Docking and Virtual screening to identify PKC agonists: potentials in anticancer therapeutics. Current Computer-Aided Drug Design (In Press). [Corresponding Author]. [Impact Factor= 1.54] [Publisher: Bentham Science Publisher].

  28. Afsana Parween, Arnish Chakraborty, Ananda Kumar Konreddy, Harapriya Chakravarty, Ashoke Sharon, Vishal Trivedi*, Chandralata Bal* (2013) Skeletal hybridization and PfRIO-2 kinase modeling for synthesis of α-pyrone analogs as anti-malarial agent. European Journal of Medicinal Chemistry, 70, 607-612. [Corresponding Author]. [Impact Factor= 3.5] [Publisher: Elsevier]

  29. Kuldeep, Niranjan Kumar V, Trivedi,V., Chhitar M Gupta, and Amogh Anant Sahasrabuddhe (2014) A novel actin-related protein in Leishmania regulates both the mitochondrial activity and flagellar assembly. Mol Microbiol. Dec 4. [Epub ahead of print] [Impact Factor= 4.96] [Publisher: Wiley]  [COVER PAGE ARTICLE].

  30.  B. Muthuraj, Rohitas Deshmukh, Vishal Trivedi*, Parameswar K. Iyer* (2014) Fluorescein-based Rapid and Highly Selective “turn-on and turn-off” sensor for copper and nitric oxide generated in-vivo. Appl. Mater. Interfaces, (in press) [Co-Corresponding Author] [Impact Factor= 5.008] [Publisher: American Chemical Society Publications].

  31. Lhouvum, K., Kshitij, B and Trivedi, V* (2014) Molecular modeling and correlation of PFI1625-peptide models of bio active peptides with antimalarial properties Med Chem Res, in press [Impact Factor= 1.6] [Publisher: Springer] [Corresponding Author].

  32. Deshmukh, R and Trivedi, V* (2014) Methemoglobin Mediated Immuno-Toxicity Modulation Of Pro-Oxidant Molecules Towards Macrophage During Malaria. PLoS One. 2014 Jul 31;9(7):e103706.[Corresponding Author].

  33. Deshmukh, R* and Trivedi, V* (2014) Role of Pro-Oxidants from Infected RBCS in Disturbing Homeostasis and Pathogenesis During Malaria. Austin J Biotechnol Bioeng - Volume 1 Issue 7. [Co-Corresponding Author]

  34. A. Mehra, Gaurav Jerath, Ramakrishnan, V and Trivedi, V* (2015) Characterization of ICAM-1 Biophore to design cyto-adherence blocking peptides. J of molecular graphics and modeling, 57C:27-35. [Corresponding Author]. [Impact Factor= 2.3] [Publisher: Elsevier].

  35.  Balaji, SN., Jawed, AM*., Singh, SJ and Trivedi, V (2015) Synthesis and antimalarial potentials of curcumin analogues containing heterocyclic rings. [Accepted for publication in Arabian Journal of chemistry]. [Impact Factor= 2.3] [Publisher: Elsevier]

  36. Malik, AH., Hussain, S., Tanwar, AS., Layek, S., Balaji, SN., Vishal Trivedi*., Iyer, PK (2015) Anionic conjugated polymer as a multi-action sensor for the sensitive detection of Cu2+, PPi, real-time ALP assaying and cell imaging. Analyst (In Press) [Co-Corresponding Author].

  37. Muthuraj, B., Layek, S., Balaji, SN., Trivedi, V*., Iyer, PK*. Multiple Function Fluorescein Probe Performs Metal Chelation, Disaggregation and Modulation of Aggregated Aβ and Aβ-Cu Complex. ACS Chemical Neuroscience [Accepted] [Co-Corresponding Author]. 

  38. Malik, AH., Hussain, S., Tanwar, AS., Layek, S., Balaji, SN., Vishal Trivedi*., Iyer, PK (2015) Anionic conjugated polymer as a multi-action sensor for the sensitive detection of Cu2+, PPi, real-time ALP assaying and cell imaging. Analyst (In Press) [Co-Corresponding Author].

  39. Chakraborty, A., Balaji, SN., Sahasrabuddhe, AA., and Trivedi, V* (2016) Cloning, Overexpression, Purification and Immunolocalization of PFD0975w from the malaria parasite Plasmodium falciparum. Infectious Disorders – Drug Targets, Vol 16, No. 2, Page number 000-000 (in Press).

  40. Saurav Paul., Ashalata Roy; Suman Jyoti Deka; Subhankar Panda; Vishal  Trivedi and Debasis Manna (2016). Rational Design of Nitrobenzofurazan Derivatives of N′-Hydroxyoximidines as potent Inhibitors of Indoleamine-2,3-Dioxygenase 1. European Journal of Medicinal Chemistry, Volume 121, 4 October 2016, Pages 364–375 [Impact Factor= 3.9] [Publisher: Elsevier].

  41. Singh, M., Pakshirajan, K and Trivedi, V (2016) Photo-inactivation of Escherichia coli and Enterococcus Hirae using methylene blue and sodium anthraquinone-2-sulphonate: effect of process parameters. 3Biotech, in Press. DOI: 10.1007/s13205-016-0487-6.

  42. Singh, M., Pakshirajan, K and Trivedi, V (2016) A study on combined effect of methylene blue and sodium anthraquinone-2-sulphonate on inactivation of Escherichia coli and Enterococcus Hirae. International Journal of Chem Tech Research, 9(6), pp 614-619.

  43. Panda, S., Roy, A., Deka, S., Trivedi, V., Manna, D. Fused Heterocyclic Compounds as Potent Indoleamine-2,3-dioxygenase 1 Inhibitors. ACS medicinal chemistry letters 7 (12), 1167-1172 [Publisher: American Chemical Society].

  44. Deka, SK., Narsimhan, M., Manna, D and Trivedi, V* Alkyl cinnamates exhibit PKC translocation and anticancer activity against breast cancer cells through induction of apoptosis following mitochondrial pathway. J Breast Cancer; 2016 December; 19(4): 358-371 [Publisher: Korean Breast Cancer Society] [Corresponding Author].

  45. Deka, SJ., Roy, A., Ramakrishnan, V., Manna, D., and Trivedi, V* (2016). Identification of danazol as PKC modulator in breast cancer cells to induce cell-cycle dysregulation and apoptosis. Chem Biol Drug Des.2017 Jun;89(6):953-963.  [Impact Factor= 2.9] [Publisher: Wiley] [Corresponding Author].

  46. Rajendran, R., Balaji, SN., Trivedi, V., and Chaturvedi, R. (2017) Isolation and quantification of antimalarial N-alkylamides from flower-head derived in vitro callus cultures of Spilanthes paniculata. J of Biosciences and Bioengineering, 2017 Mar 31 pii S1389-1723 [Impact Factor= 1.9] [Publisher: Elsevier].

  47. Deka, SJ., Gorai, S., Manna, D., and Trivedi, V* (2017) Evidence of PKC Binding and Translocation to explain the anticancer mechanism of chlorogenic acid in breast cancer cells. Current Molecular Medicine,... [Impact Factor= 2.9] [Publisher: Bentham Science publisher]

  48. Dalapati,R., Balaji, SN., Trivedi, V., Khamari, L and Biswas, S* (2017) A dinitro-functionalized Zr(IV)-based metal-organic framework as colorimetric and fluorogenic probe for highly selective detection of hydrogen sulphide. Sensors & Actuators: B. Chemical, 2017, 245, 1039.  [Impact Factor= 4.75] [Publisher: Elsevier].

  49. Saurav Paul, Ashalata Roy, Suman Jyoti Deka, Subhankar Panda, Gopal Narayan Srivastava, Vishal Trivedi and Debasis Manna* (2017) Synthesis and evaluation of oxindoles as promising inhibitors to the immunosuppressive enzyme indoleamine 2,3-Dioxygenase 1. MedChemMed (In Press).

  50. Nirmalya Pradhan, Saurav Paul, Ashalata Roy, Suman Jyoti Deka, Vishal Trivedi and Debasis Manna* (2017) Identification of Substituted 1H-Indazoles as Potent Inhibitors for Immunosuppressive Enzyme Indoleamine 2,3-Dioxygenase 1. ChemistrySelect 2017, 2, 5511 – 5517

  51. Soutick Nandi a, Helge Reinschb, Sooram Banesh,c Norbert Stock b, Vishal Trivedi,c Shyam Biswasa,* Azide-functionalized Al(III)-based CAU-10 metal-organic framework as a fluorescent turn-on probe for the selective and sensitive detection of H2S (2017) Daltan Transduction (in Press).

  52. Saha, Abhishek; Panda, Subhankar; Pradhan, Nirmalya; Kalita, Kangkan, Trivedi, Vishal; Manna, Debasis. Azidophosphonate chemistry as route to a novel class of vesicle forming phosphonolipids. Chemistry?A European Journal 24 (5), 1121-1127.

  53. Deka, SJ., Roy, A., Manna, D., and Vishal Trivedi# (2018) Integrating Virtual Screening and Biochemical Experimental approach to identify potential anti-cancer agents from Drug Databank.Journal of Bioinformatics and Computational Biology (In Press) [Corresponding Author].

  54. Aniruddha Das, Sooram Banesh, Vishal Trivedi and Shyam Biswas* (2018). Extraordinary Sensitivity for H2S and Fe(III) Sensing in Aqueous Medium by Al-MIL-53-N3 Metal-Organic Framework: In Vitro and In Vivo Sensing Applications. Dalton Transactions, 2018, 47, 2690 - 2700.

  55. Deka, SJ., Trivedi, V* (2018) Potentials of PKC in cancer progression and anticancer drug development. Curr Drug Discov Technol. Feb 2018. doi: 10.2174/1570163815666180219113614. [Epub ahead of print] [Corresponding Author].   

  56. Soutick Nandi, Sooram Banesh, Vishal Trivedi and Shyam Biswasa,*(2018). A dinitro-functionalized metal?organic framework featuring visual and fluorogenic sensing of H2S in living cells, human blood plasma and environmental samples. Analyst 143 (6), 1482-1491.

  57. Deka, SJ., Gorai, S., Manna, D., Trivedi, V*. Biochemical studies and Virtual Screening of Phytochemical reservoir from northeastern Indian plants to identify anti-cancer agents. Journal of Biologically Active Products from Nature (In press). [Publisher: Taylor and Francis] [Corresponding Author].

  58. Vimee Raturi., Kumar Abhishek, Subhashis Jana, Subhendu Sekhar Bag and Trivedi, V*(2018). Virtual Screening, Molecular modelling and biochemical studies to exploit PF14_0660 as a target to identify novel anti-malarials. Letter in Letters in Drug Design & Discovery (Publisher: Benthan Sciences) [Corresponding Author].



Antimicrobial Peptides. 

Inventors: Vibin Ramakrishnan, Prakash Kishore Hazam, Nitin Chaudhary, Vishal Trivedi and Gaurav Jerath. Patent No. 333/KOL/2015. Dated 26.03.2015






Last Updated (Jan, 2018)


IITG Front gate Malaria Life cycle RBC Aggregation NASI Medal