Publications


129
Kumar A, Dhillon A, Manjegowda MC, Singh N, John Mary DJS, Kumar S, Modi D, Limaye AM [2021] Estrogen suppresses HOXB2 expression via ERα in breast cancer cells. Gene. 145746

128
Patil SS, Shinduja R, Puttahonnappa SK, Phukan S, Kumar S, Sengupta PP, Amachawadi RG, Raut A, Roy P, Syed A, Marraiki N, Elgorban AM, Al-Harthi HF, Bahkali AH, Shivamallu C, Shiva Prasad K, [2021] A systematic review and meta-analysis on the prevalence of infectious diseases of Duck: A world perspective. Saudi Journal of Biological Sciences.

127
Patel A, Dey S, Shokeen K, Karpinski TM, Shivaprakasam S, Kumar S, Manna D, [2021] Sulfonium-based liposome-encapsulatedantibiotics deliver a synergistic antibacterialactivity. RSC Med.Chem.


125
Joshi M, Puvar A, Kumar D, Ansari A, Pandya M, Raval J, Patel Z, Trivdi P, Gandhi M, Pandya L, Patel K, Savaliya N, Bagatharia S, Kumar S, Joshi C, [2021] Genomic variations in SARS-CoV-2 genomes from Gujarat: Underlying role of variants in disease epidemiology. Front. Genet. 12:586569.


123
Otani Y, Sur H, Rachaiah G, Namagiri S, Chowdhury A, Lewis CT, Shimizu T, Gangaplara A, Wang X, Vézina A, Maric D, Jackson S, Yan Y, Zhengping Z, Ray-Chaudhury A, Kumar S, Ballester LY, Chittiboina P, Yoo JY, Heiss J, Kaur B, Kumar Banasavadi-Siddegowda Y, [2021] Inhibiting protein phosphatase 2A increases the antitumor effect of protein arginine methyltransferase 5 inhibition in models of glioblastoma. Neuro Oncol. noab014.














108
Joshi M, Puvar A, Kumar D, Ansari A, Pandya M, Raval J, Patel Z, Trivdi P, Gandhi M, Pandya L, Patel K, Savaliya N, Bagatharia S, Kumar S, Joshi C, [2020] Genomic variations in SARS-CoV-2 genomes from Gujarat: Underlying role of variants in disease epidemiology. bioRxiv


106
Gowthaman V, Kumar S*, Koul M, Dave U, Gopala Krishna Murthy TR, Palanivelu M, Tiwari R, Karthik K, Dhama K, Michalak I, Joshi SK* , [2020] Infectious Laryngotracheitis: Etiology, Epidemiology, Pathobiology, and Advances in Diagnosis and Control – A Comprehensive Review. Vet Q. 40(1): 140–161.

105
Devi YD, Devi A, Gogoi H, Gogoi B, Dehingia B, Doley R, Buragohain AK, Singh S, Borah PP, Rao CD, Ray P, Varghese GM, Kumar S, Namsa ND, [2020] Exploring rotavirus proteome to identify potential B- and T-cell epitope using computational immunoinformatics. Heliyon. 6: 12, e05760.




101
Sarmah H, Shah M, Pathak M, Barman NN, Koul M, Gupta A, Sahariah PJ, Neher S, Das SK, Gogoi SM, Kumar S*, [2020] Pathodynamics of circulating strains of duck enteritis virus: A step forward to understand its pathogenesis. Avian Dis. 64(2):166-173.




























73
Patwa R, Soundararajan N, Mulchandani N, Bhasney SM, Shah M, Kumar S, Kumar A, Katiyar V, [2018] Silk Nano-Discs: A Natural Material for Cancer Therapy. Biopolymers. 109(11):e23231








65
Barman NN, Choudhury B, Kumar V, Koul M, Gogoi SM, Khatoon E, Chakraborty A, Basumastary P, Barua B, Rahman T Das SK, Kumar S*, [2017] Incidence of elephant endotheliotropic herpesvirus in Asian elephants in India. Vet Micro. 208:159-163.





60








52
Barman NN, Bora DP, Khatoon E, Mandal S, Rakshit A, Rajbongshi G, Depner K, Chakraborty A, Kumar S, [2016] Classical Swine fever in wild hog: report of its prevalence in Northeast India. Transbound Emerg Dis. 63(5):540-7.





















31
Adam V, Crosariol M, Kumar S, Ge M, Czack S, Roy S, Haczku A, Tretiakova A, Wilson JM, and Limberis M, [2014] AAV9-mediated airway expression of antibody protects old and immunodeficient mice against influenza. Clin Vaccine Immunol.21(11):1528-1533.





26
Pena L, Sutton T, Chockalingam A, Kumar S, Angel M, Chen H, Li W, Perez DR, [2013] Influenza viruses with rearranged genomes as live-attenuated vaccines. J Virol: May;87(9):5118-27.

25
Nayak B, Nayak S, Paldurai A, Kumar S, De Nardi R, Terregino C, Collins PL, Samal SK, [2013] Evaluation of the genetic diversity of avian paramyxovirus-4. Virus Res. 171(1):103-10.


























GenBank Submissions


Patents


Presentations in Conferences

55

Kumar S, [2021] Invited talk on “Brief overview on the blood borne pathogens” 26th March 2021, Sri Venkateswara College of Engineering Pennalur, Sriperumbudur tk, Tamil Nadu-602117.


54

Kumar S, [2021] Invited lecture on “Discovery of Hepatitis C Virus” at INSTITUTE OF ADVANCED STUDY IN SCIENCE AND TECHNOLOGY (IASST) Govt. of India, Guwahati. 28th Feb 2021 on the occasion of National Science Day.


53

Kumar S, [2021] Invited lecture on “Understanding the biology of avian paramyxovirus for the development of recombinant vaccine” in the Online International Training Course on “Biotechnological Approaches in Animal Research and Disease Diagnosis.” College of Animal Biotechnology Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana-141004, Punjab. 12 February 2021.


52

Kumar S, [2021] Invited lecture on “Prospects of viral vectored vaccines” as subject matter expert during the DBT training program on “Skill development in viral disease diagnosis and prophylaxis”. College of Animal Biotechnology Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana-141004, Punjab Jan 5-11, 2021.


51

Kumar S, [2020] “Current understanding of SARS-COV-2 biology” Invited webinar, School of life sciences and biotechnology, Adamas University 21st May 2020.


50

Kumar S, [2020] Invited webinar on “Understanding the biology of Avian Paramyxovirus for the development of recombinant vaccine with special reference to COVID-19. 27th Nov 2020 Assam Don Bosco University.


49

Kumar S, [2020] Invited webinar on “Understanding the biology of avian paramyxovirus for the development of recombinant vaccine ”. 2th August 2020, Department of Physics, IIT Guwahati.


48

Kumar S, [2020] Invited webinar on “Nobel Prize 2020 in medicine”. 20th Oct 2020, Department of Physics, IIT Guwahati.


47

Kumar S, [2020] Invited webinar on “Nanostructured Materials and their Applications in Nanotechnology”. 28th Oct 2020, Department of Physics, IIT Guwahati.


46

Kumar S, [2019] Newcastle disease virus based approach for the development of diagnostics and vaccine against pathogens. Invited talk Microbiology Department, GMCH, Guwahati, 18th July 2019.


45

Kumar S, [2019] Avian paramyxovirus friend or foe? (Lecture Series) CAAST-ACLH on 23rd March 2019 at Indian Veterinary Research Institute, Izatnagar, UP.


44

Kumar S, [2019] Avian paramyxovirus friend or foe? (Key note talk) Research Conclave on 15th March 2019 at Indian Institute of Technology Guwahati.


43

Kumar S, [2019] Avian paramyxovirus and its use as a vaccine vector (Lead Paper) 19th Indian Veterinary Congress, XXVI Annual Conference of IAAVR and National Symposium is being organized from 1-2 February 2018 at West Bengal University of Animal & Fishery Sciences.


42

Kumar R, Kumar V, Kekungu P and Kumar S, [2018] Diagnostics and vaccine development of classical swine fever virus based on recombinant Newcastle disease viral vector at the Indian Association of Veterinary Microbiologists, Immunologists and Specialists in Infectious Diseases (IAVMI) in Sri Venkateswara Veterinary University (SVVU), Tirupati. 29-31st Jan 2018. (Best poser award)


41

Kumar S, [2017] Invited talk on Newcastle disease virus as a vector for vaccines and diagnostics, at the Institute of Sciences, Nirma University, Ahmedabad, Gujrat (26th Dec 2017).


40

Kumar S, [2017] Invited talk on Development of genetically engineered live viral vaccines, at the College of Veterinary Sciences and Animal Husbandry, Anand Agricultural University, Anand 388110, Gujrat (21st Dec 2017).


39

Kumar S, [2017] Application of nanotechnology in animal disease diagnosis, in Advances in Molecular techniques in Animal Health and Production with particular reference to pigs, ICAR-NRC on Pig, Rani, Guwahati, Assam (24th Nov to 14th Dec 2017)


38

Nath B, Kumar S, [2017] Improved Japanese encephalitis virus vaccine using recombinant Newcastle disease virus as a vector. VIROCON 2017, 26th National Conference of Indian Virological Society (IVS) at Nitte University, Mangalore, India, December 7- 9, 2017. (2nd best Poster Presentation, Medical Virology Section)


37

Kumar S, [2017] Newcastle disease virus as a tool for poultry vaccine and Diagnostics, lead speaker XXXIV Annual Conference of Indian Poultry Science Association (IPSACON 2017) on 28-30 November 2017 at NIMHANS Convention Centre, Bengaluru.


36

Kumar S, [2017] Newcastle disease virus as a tool for animal vaccine and diagnostics, lead paper talk on International Workshop on One Health and Sustainable Economic Development 13th to 19th November, 2017 School of Animal Biotechnology and School of Public Health and Zoonoses Guru Angad Dev Veterinary and Animal Sciences University Ludhiana, Punjab- 141004.


35

Das M and Kumar S, [2017] Independent evolution of genotype XIII newcastle disease viruses from india: a panzootic threat, talk on the "National Seminar on Opportunities and challenges of translational research in the frontier areas of Animal Biotechnology and V Annual Convention of SVSBT". (SVSBT) at OUAT 23rd and 24th September (Best Oral Award).


34

Das M and Kumar S, [2016] “Recombinant Newcastle disease virus as a vaccine vector for animal and human pathogens”. Invited talk at school of Biotechnology GADVASU, Ludhiana on 20th Oct 2016.


33

Das M and Kumar S, [2016] Molecular characterization of an apoptotic strain of Newcastle disease virus from Northeast India. Biology and Molecular Pathogenesis of Viruses, organized at MCB at IISC on 20-21st June (Best Poster Award).


32

Kumar S, [2016] Reverse genetics of Newcastle disease virus. National conference on new avenues in microbiology and biotechnology challenges and prospects at WBSU, Barasat, West Bengal on 18th-19th March. (Lead Speaker)


31

Kumar S, [2016] Reverse genetics of Newcastle disease virus an innovative tool for the development of recombinant vaccine. XXIX annual convention of Indian association of veterinary microbiologists, immunologist and specialist in infectious diseases at AAU Khanapara and NRCP Rani, Guwahati on 12-14th Feb 2016. (Lead paper)


30

Kumar U and Kumar S, [2015] In vitro assessment of antitumor potential of Newcastle disease virus in human cancer cells. Society of biological chemist India at the, 14 FAOBMB congress and 84th annual meeting at Hyderabad from 27th Nov- 30th Nov (Best Poster Award).


29

Kumar S, [2015] Newcastle disease virus: Reverse genetics approach to understand its biology. VIROCON, XXIV National Conference of Indian Virological Society at NEIGRIHMS, Shillong Meghalaya. 8th- 10th Oct. (Lead Paper).


28

Kumar S, [2015] “Inspire faculty award for Newcastle disease virus” Networking-cum-Discussion meet at the Tezpur University, Assam. 20-21 March 2015. (Poster presentation).


27

Kumar R and Kumar S, [2014] “Molecular Characterization of classical swine fever virus following its adaptation in porcine kidney cells”. XXIII National conference on “Recent Trends in Virology Research in the Omics Era” at Indian Virological Society. Dec 18-20, 2014. (Poster presentation).


26

Das M and Kumar S, [2014] “Molecular characterization of Newcastle disease virus isolated from Northeast India”. XXIII National conference on “Recent Trends in Virology Research in the Omics Era” at Indian Virological Society. Dec 18-20, 2014. (Poster presentation).


25

Kumar U and Kumar S, [2014] “Genotypic and pathotypic characterization of virulent Newcastle disease virus isolated from Eastern part of India”. XXIII National conference on “Recent Trends in Virology Research in the Omics Era” at Indian Virological Society. Dec 18-20, 2014. (Poster presentation).


24

Kumar S, [2014] “Peptides in Immunology”. Two days workshop on “PEPTIDE DRUGS: MODELING TO PRACTICE” organized under technical education quality improvement program (TEQIP) at Indian Institute of Technology Guwahati 7-8th Nov 2014. (Oral presentation).


23

Ganar K and Kumar S, [2014] Cloning and expression of nucleocapsid protein gene of Newcastle disease virus. The international conference on host-pathogen interaction, Hyderabad, India. 12-15th July 2014 (Poster presentation).


22

Kumar S, Nayak B, Collins PL, Samal SK, [2011] Reverse genetic study of avian paramyxovirus type-3. The American Veterinary Medical Association Meeting in St Louis, USA, 16th -19th July, 2011 (Oral presentation).


21

Samal S, Kumar S, Khattar SK, Samal SK, [2011] A single amino acid change glutamine to arginine (Q114R) in cleavage site motif of Newcastle disease virus fusion protein attenuates the virus. The American society for virology meeting (Minneapolis) July 16-20, 2011(Oral presentation).


20

Kumar S, Samal SK, [2010] Characterization and Complete Genome Sequence of Avian Paramyxovirus Serotype-3. Bioscience Day 9th Nov, University of Maryland (Poster presentation).


19

Kumar S, Nayak B, Collins PL, Samal SK, [2010] Evaluation of the Newcastle disease virus F and HN proteins in protective immunity using a recombinant avian paramyxovirus type-3 vector in chickens. Conference of Research Workers on Animal Diseases (CRWAD) meeting, Chicago, Illinois, USA, December 5-7, 2010 (Oral presentation).


18

Nayak B, Kumar S, Dias F, Paldurai A, Samuel A, Xiao S, Samal SK, [2010] Antigenic relationships among avian paramyxovirus serotypes. CRWAD meeting, Chicago, Illinois, USA, December 5-7, 2010 (Oral presentation).


17

Kumar S, Collins PL, Samal SK, [2010] Recovery of avian paramyxovirus type- 3 from cDNA, Graduate Research Interaction Day at University of Maryland on 7th April 2010 (Oral presentation).


16

Paldurai A, Kumar S, Kim SH, Collins PL, Samal SK, [2010] Role of genome length in Newcastle disease virus pathogenesis and virulence. The American society for virology meeting (Montana) July 17-21, 2010 (Oral presentation).


15

Xiao S, Subbiah M, Kumar S, De Nardi R, Terregino C, Collins PL, Samal SK, [2010] Complete genome sequences of avian paramyxovirus serotype 6 prototype strain Hong Kong and a recent novel strain from Italy: evidence for the existence of subgroups within the serotype, The American society for virology meeting (Montana) July 17-21, 2010 (poster presentation).


14

Samal S, Khattar SK, Kumar S, Samal SK, [2010] Role of N linked glycosylation of Newcastle Disease virus fusion protein in virulence and viral pathogenicity. The American society for virology meeting (Montana) July 17-21, 2010 (Oral presentation).


13

Nayak B, Kumar S, Dinapoli JM, Paldurai A, Perez DR, Collins PL and Samal SK, [2009] Immunogenicity and protective efficacy of recombinant Newcastle disease virus expressing avian influenza virus HA, NA and M2 surface proteins in chickens, CRWAD meeting, Chicago, Illinois, USA, December 6-8, 2009 (Oral presentation).


12

Kumar S, Collins PL, Samal SK, [2009] Complete genome sequence and characterization of avian paramyxovirus serotype-3. The American Veterinary Medical Association Meeting in Seattle, USA, 11th -14th July, 2009 (Poster presentation).


11

Kumar S, Collins PL, Samal SK, [2009] Characterization and Complete Genome Sequence of Avian Paramyxovirus Serotype-3, Graduate Research Interaction Day at University of Maryland on 13th April 2009 (Oral presentation).


10

Kumar S, Collins PL, Samal SK, [2008] Pathogenicity and complete genome sequence analysis of avian paramyxovirus serotype-3, The American society for virology meeting held at Cornell University (Ithaca, NY), USA on 12-16th July 2008 (Oral presentation).


09

Kumar S, Collins PL, Samal SK, [2007] Characterization of avian paramyxovirus serotype-3. The American society for virology meeting at Oregon State University (Corvallis) on 14-18th July 2007 (Poster presentation).


08

Kumar S and Samal SK, [2007] Molecular characterization and pathogenicity of avian paramyxovirus type-3, Department of Veterinary Medicine at University of Maryland (UMD), fall seminar series 2007 (Oral presentation).


07

Kumar S, Ahi YS, Salunkhe SS, Koul M, Tiwari AK, Gupta PK, Rai A, [2006] Cloning of infectious Bursal disease virus VP2 genes in a bicistronic mammalian expression vector for use as DNA vaccine (10th ADNAT convention) held at Centre for cellular and molecular biology (CCMB), Hyderabad, India, 23-24 February, 2006 (Poster presentation).


06

Kumar S, [2006] Oral tolerance in division of Veterinary immunology, Indian Veterinary Research Institute, India (Oral presentation).


05

Kumar S, [2006] Self replicating RNA vaccines in division of Veterinary biotechnology Indian Veterinary Research Institute, India (Oral presentation).


04

Kumar S, [2003] Gene therapy solving enigma of cancer in National Conference on Plant Biotechnology for Agriculture and Rural Development, Basara, India, Feb 18-19, 2003 (Oral presentation).


03

Kumar S, [2003] 50 years of DNA in national science day celebration 2003 Marathwada Agricultural University, Parbhani, India (Oral presentation).


02

Kumar S, Dhumal MV, Siddiqui MF, [2002] A review on non-conventional feed resources for sustainable livestock production, in conference at Shere-Kashmir Agricultural University (India) 2002 (Oral presentation).


01

Kumar S, Dhumal MV, Siddiqui MF, [2002] Emerging diseases of poultry, in poultry scientists and farmers meet, College of Veterinary Sciences, Karnataka (India), organized by the world poultry science association Nov 22, 2002 (Oral presentation).



Research

Background

The paramyxoviruses include viruses that are isolated from many species of terrestrial, avian and aquatic animals. The group includes many important pathogens of humans such as measles virus, human respiratory syncytial virus, human parainfluenza viruses, Nipah virus and Hendra virus and animals such as canine distemper virus and Newcastle disease virus. Newcastle disease virus (NDV) is the prototype member of this family and is a leading cause of respiratory disease in avian species. It leads to huge economic losses to the poultry industry in India. Our laboratory focuses mainly on understanding the biology of avian paramyxovirus and development of vaccine against them using reverse genetics system.


Research Interests

  • Identification of molecular determinants of avian paramyxovirus virulence.
  • Reverse genetics study of avian paramyxoviruses: Newcastle disease virus as a model.
  • Vaccine development against avian paramyxoviruses using reverse genetics system.
  • Viral vector study- Avian paramyxoviruses and adenoviruses.
  • Oncolytic activity of Avian paramyxoviruses.

Current Fundings


Book Chapters