2025-09-16

Researchers the Department of Biosciences and Bioengineering (BSBE), IIT Guwahati have developed a new method to produce recombinant human insulin using a safe and efficient bacterial system called Pseudomonas fluorescens. The team is led by Professor Veeranki Venkata Dasu, and Dr. Ansuman Sahoo, Former Ph.D. and PMRF. Futher, the team consists of Prabir Kumar Das, Dr. MSRC Murthy and Prof. Sanjukta Patra. Unlike conventional E. coli, yeast, or mammalian systems, this safe, efficient method overcomes their limitations and enables simpler downstream processing aimed at lowering production cost. Beyond insulin, the platform offers potential for producing other therapeutic proteins and industrial enzymes, marking a significant step toward accessible healthcare. The developed bioprocess has been granted two Indian patents (Patent No. 568947, Application No. 202431045821. Date of Grant: 22-07-2025; Patent No. 536416, Application No. 202331058235. Date of Grant: 01.05.24).