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to Physical Cell Biology Course Page Course Details Code: BT 630 Title: Physical Cell Biology Credits: 3
0 0 6 Instructor: B. Anand Duration: Mon (10-10.55); Tue (11-11.55); Fri (9-10) Venue: 1006 Pre-requisite: Nil Motto: To obtain quantitative insights on the underlying biological complexity by the application of physical models Syllabus: Space
and time inside a living cell, their scales and hierarchy;
Model systems: haemoglobin, bacteriophage, E. coli, yeast, fruit
fly and man; Mechanical and chemical equilibrium in a living cell;
Applications of entropy and
statistical mechanics; Two state systems; Random walks; Protein
electrostatics; Beam theory
of cellular architecture; Biological membranes: springiness, shape
and
energetics; Hydrodynamics of water and fluid dynamics of blood;
Low Reynolds
number world; Diffusion in the cell; Life in the crowded and
disordered
environments; Rate equations in the cell; Molecular motors,
biological electricity and the
Hodgkin-Huxley model.
References: 1. R. Philips, J. Kondev and J. Theriot, Physical
Biology of the Cell, 1st Edn., Garland Science, 2009. 2. P. Nelson, Biological Physics, 1st Edn., W.
H. Freeman, 2007. 3. B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts and P. Walter, Molecular Biology of the Cell, 5th Edn., Garland Science, 2007. 4. Milo & Philips, Cell Biology by the Numbers, Garland Science, 2016 5. Contemporary Journal Articles Resources: Please visit here for regular updates on course information [INTRANET ONLY] |