Mechanistic Approaches to Biology Lab

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Welcome to Physical Cell Biology Course Page

Course Details

Code: BT 630

Title: Physical Cell Biology

Credits: 3  0  0  6 

Instructor: B. Anand

Duration:  Mon (10-10.55); Tue (11-11.55); Fri (9-10)

Venue:  1006

Pre-requisite: Nil

Motto: To obtain quantitative insights on the underlying biological complexity by the application of physical models


Space and time inside a living cell, their scales and hierarchy; Model systems: haemoglobin, bacteriophage, E. coli, yeast, fruit fly and man; Mechanical and chemical equilibrium in a living cell; Applications of entropy and statistical mechanics; Two state systems; Random walks; Protein electrostatics; Beam theory of cellular architecture; Biological membranes: springiness, shape and energetics; Hydrodynamics of water and fluid dynamics of blood; Low Reynolds number world; Diffusion in the cell; Life in the crowded and disordered environments; Rate equations in the cell; Molecular motors, biological electricity and the Hodgkin-Huxley model.


1. R. Philips, J. Kondev and J. Theriot, Physical Biology of the Cell, 1st Edn., Garland Science, 2009.

2. P. Nelson, Biological Physics, 1st Edn., W. H. Freeman, 2007.

3. B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts and P. Walter, Molecular Biology of  the Cell, 5th Edn., Garland Science, 2007.

4. Milo & Philips, Cell Biology by the Numbers,  Garland Science, 2016

5. Contemporary Journal Articles

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2010 Indian Institute of  Technology Guwahati
Designed & Maintained by B. Anand
Last Updated Jan, 2018