Mechanistic Approaches to Biology Lab


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  • Nimkar S, Anand B (2020) Cas3/I-C Mediated Target DNA Recognition and Cleavage during CRISPR Interference are Independent of the Composition and Architecture of Cascade Surveillance Complex. Nucleic Acids Res. 48: 2486–2501 [Article online]. Preprint at BioRxiv 666776 [Preprint online]

  • K.N Yoganand, Muralidharan M, Nimkar S, Anand B (2019) Fidelity of Prespacer Capture and Processing is Governed by the PAM Mediated Interactions of Cas1-2 Adaptation complex in CRISPR-Cas type I-E system. J. Biol. Chem. 294: 20039-20053 [Article online]. Preprint at BioRxiv 602623 [Preprint online] 

  • Sharma H, Anand B (2019). Ribosome assembly defects subvert initiation Factor3 mediated scrutiny of bona fide start signal. Nucleic Acids Res. 47: 11368–11386 [Article online]. Preprint at BioRxiv 498592 [Preprint online]

  • Katla S, Yoganand K.N.R, Hingane S, Ranjith Kumar C.T, Anand B, Senthilkumar S (2019). Novel glycosylated human interferon alpha 2b expressed in glycoengineered Pichia pastoris and its biological activity: N-linked glycoengineering approach. Enzyme Microb. Technol.128: 49-58. [Article online]

  • Katla S, Karmakar B, Tadi SRR, Mohan N, Anand B, Pal U, Sivaprakasam S (2019). High level extracellular production of recombinant human interferon alpha 2b in glycoengineered Pichia pastoris: culture medium optimization, high cell density cultivation and biological characterization. J. Appl. Microbiol. 126:1438-1453 [Article online]

  • Punetha A, Yoganand KNR, Nimkar S, Anand B (2018). Cutting it Right: Plasticity and Strategy of CRISPR RNA Specific Nucleases. Proc. Indian Natn. Sci. Acad. 84: 455-477 [Article online]

  • Yoganand K N R, Sivathanu R, Nimkar S, Anand B (2017). Asymmetric Positioning of Cas1-2 Complex and Integration Host Factor Induced DNA Bending Guide the Unidirectional Homing of Protospacer in CRISPR-Cas Type I-E system Nucleic Acids Res. 45: 367-381 [Article online]

  • Sharma H, Anand B (2016). Fluorescence Bimolecular Complementation Enables Facile Detection of Ribosome Assembly Defects in Escherichia coli RNA Biol., 13: 872-882  [Article online]

  • Punetha A, Sivathanu R, Anand B (2014). Active Site Plasticity Enables Metal Dependent Tuning of Cas5d Nuclease Activity in CRISPR-Cas Type I-C System Nucleic Acids Res. 42: 3846-3856 [Article online]

  • Gulati M, Jain N, Anand B, Prakash B, Britton RA (2013).  Mutational analysis of the ribosome assembly GTPase RbgA provides insight into ribosome interaction and ribosome-stimulated GTPase activation. Nucleic Acids Res. 41: 3217-3227 [pdf]

  • Anand B, Majumdar S, Prakash B (2013).  The Structural Basis Unifying Diverse GTP Hydrolysis Mechanisms. Biochemistry 52:1122–1130 [pdf]

  • Anand B, Surana P, Prakash B (2010).  Deciphering the Catalytic Machinery in 30S Ribosome Assembly GTPase YqeH. PLoS ONE 5(4): e9944 [pdf]

  • Anand B, Surana P, Bhogaraju S, Pahari S, Prakash B (2009).  Circularly permuted GTPase YqeH binds 30S ribosomal subunit: Implications for its role in ribosome assembly. Biochem. Biophys. Res. Commun. 386:602-606. [pdf]

  • Anand B, Verma SK, Prakash B (2006).  Structural stabilization of GTP-binding domains in circularly permuted GTPases: Implications for RNA binding. Nucleic Acids Res. 34:2196 - 2205. [pdf]

  • Anand B, Gowri VS, Srinivasan N (2005). Use of multiple profiles corresponding to a sequence alignment enables effective detection of remote homologues. Bioinformatics 21:2821-2826. [pdf]

  • Anand B, Seema N, Sandhya S, Srinivasan N (2004). Influence of protein structural similarities in adding value to genome data. Indian Journal of Biotechnology 3:486-494. [pdf]

  • Pandit, SB, Bhadra R, Gowri VS , Balaji S, Anand B, Srinivasan N (2004). SUPFAM web resources of sequence superfamilies of protein domains.  BMC Bioinformatics 5:28. [pdf]

  • Pandit SB, Bhadra R, Gowri VS, Balaji S,  Anand B ,  Srinivasan N (2004). SUPFAM (release 1.4). Nucleic Acids Res. http://www3.oup.co.uk/nar/database/summary/219 [on-line publication]

  • Gowri VS, Pandit SB, Anand B, Srinivasan N, Balaji S (2004). PALI release 2.2: A database of aligned homologous protein structures and phylogenetic trees integrated to related sequences. Nucleic Acids. Res. http://www3.oup.co.uk/nar/database/summary/274 [on-line publication]



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Designed & Maintained by B. Anand
Last Updated December,  2019