BT 205	Cell and Molecular Biology	3-0-0-6
Pre-requisites :BT 101 Objective The aim of this core course is to provide a detailed insight into the concepts of molecular biology and its mechanisms that control cell functions along with a sense of its complex regulatory mechanisms. Syllabus Cell organization and subcellular structures; structure and properties of nucleic acids; organization of prokaryotic and eukaryotic genomes; mechanisms of DNA replication; mechanism of DNA recombination; transcription, eukaryotic RNA splicing and processing; translation; regulation of gene expression; cell signaling; programmed cell death; oncogenes; genes in differentiation and development. Text Books 1. D. L. Nelson and M. M. Cox, Lehninger Principles of Biochemistry, 6th Ed., Macmillan Worth, 2012. 2. B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts and P. Walter, Molecular Biology of the Cell, 6th Ed., Garland Publishing, 2015. 3. H. Lodish, A. Berk, C. A. Kaiser, M. Krieger, M. P. Scott, A Bretscher, H. Ploegh, and P. Matsudaira, 6th Ed., W. H. Freeman & Co., 2007. References 1. B. Lewin, Genes XI, International Edition, Pearson Education, 2014. 2. B. R. Glick and J.J. Pastemak, Molecular Biotechnology: Principles and applications of recombinant DNA, 4rth Ed., ASM Press, 2010. 3. Jordanka Zlatanova, Kensal van Holde, Molecular Biology, (1st Ed), 2015. 4. Nancy Craig, Rachel Green, Carol Greider, Gisela Storz, Cynthia Wolberger, and Orna Cohen-Fix Molecular Biology, Principles of Genome Function (2nd Ed), 2014.