A Look Back At Our History
This is my Education and Experience
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2008
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Apr
Assistant Professor, IIT Guwahati
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2015
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Associate Professor, IIT Guwahati
aug
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2019
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feb
Professor, IIT Guwahati
My Research
Exploring Innovation: Unveiling Insights Through Research
Research Interest
My research interest is centered mainly on synthetic organic chemistry and chemical biology. The first direction of research includes the development of newer methodologies for the synthesis of peptides, azapeptides, sulfonamides, hydroxamic acids, urea based peptides etc. and also the development of newer coupling reagents for peptide synthesis and other organic reactions.
We have developed some Oxyma based recyclable coupling reagents. Selected examples:-
Some Important Applications of o-NosylOXY:-
In parallel, we are also working on the disruption of amyloid aggregation. Amyloidoses,
e.g.,
Alzheimer’s disease, diabetes type II, Parkinson’s disease, etc., are major age related
problems
at present. Knowledge on the evolution, propagation, and remedy for these diseases are
limited.
We are working on strategies development for Amyloid disruption. Side by side, works on
the
elucidation of the pathway of amyloid formation is also in progress.
β-Sheet Breaker Hybrid peptide (BSBHP) against Alzheimer's disease:
We are also investigating the supramolecular self-assembly of small peptides, Shown below:-
Mechanistic pathway : β-Sheet Breaker Hybrid peptide (BSBHP) disrupts amyloid aggregates.
We have synthesized four 38 membered peptide, Aβ38 and three of its proline mutants and studied their aggregation behavior.
MEET MY TEAM
This is the team that is working with me
Mr. Altaf Hussain Kawa
Graduation: B.Sc. Chemistry(H) at A.M.U Aligarh
Post-Graduation: M.Sc. Chemistry at A.M.U Aligarh
Ph.D: Department of Chemistry, IIT GUWAHATI, Since June, 2018 ; Area of research: Development of Artificial Proteasome; E-mail-altaf@iitg.ac.in
Mr. Avishek Sarkar
Graduation: B.Sc. Chemistry(H) at APC College, West Bengal State University
Post-Graduation: M.Sc. Chemistry at IIT(ISM) Dhanbad
Ph.D: Department of Chemistry, IIT GUWAHATI, Since June, 2020; Area of research: Strategies for amyloid inhibition; E-mail-asarkar@iitg.ac.in
Mr. Sukesh Shill
Graduation: B.Sc. Chemistry(H) at Arya vidyapeeth, Gauhati University
Post-Graduation: M.Sc. Chemistry, Cotton University
Ph.D: Department of Chemistry, IIT GUWAHATI,Since june, 2019; Area of research: Strategies for amyloid inhibition; E-mail-s.shill@iitg.ac.in
Mr. T Ngamgoumang Baite
Graduation: BSc. Chemistry(H) at Kirorimal college, Delhi University
Post-Graduation: MSc. Chemistry at Manipur University
Ph.D: Department of Chemistry, IIT GUWAHATI, Since Dec, 2023; Area of research: ; E-mail-t.baite@iitg.ac.in
MY GALLERY
Journey Through Moments: A Look Back at Our Gallery
