Contact
Research interests
Academic
Projects
Publications
Students & Staff
 
Contact

Dr. Utpal Bora
Associate Professor
Biomaterials and Tissue Engineering Laborotory
Department of Biotechnology
Indian Institute of Technology Guwahati
Assam India
PIN 781039

Email: ubora@iitg.ernet.in
Tel: +91 361 2582215
Fax: +91 361 2582249
    
Research interests

Biomaterials, Nanotechnology, Drug Delivery and Tissue Engineering   
 
Academic

Professional track

Associate Professor, Department of Biotechnology, IIT Guwahati, North Guwahati, Assam (September, 2008 - Present).

Assistant Professor, Department of Biotechnology, IIT Guwahati, North Guwahati, Assam (May, 2006 – September 2008).

Senior Lecturer, Department of Biotechnology, IIT Guwahati, North Guwahati, Assam (December, 2004 – May 2006).

CSIR Fellow, Institute of Genomics and Integrative Biology, Delhi (September 1999 – December 2004).

JRF, National Bureau of Animal Genetic Resources (ICAR), Karnal (December 1998-July 1999)

Department of Biotechnology, Govt. of India Fellow, Assam Agricultural University (August 1996-August 1998)

Education

Ph.D. (Biotechnology) – Institute of Genomics and Integrative Biology, Delhi (degree awarded by GGS Indraprastha University, Delhi).

M.Sc.(Agril. Biotechnology) - Assam Agricultural University, Jorhat, 1998, First Class.

B.Sc.(Agril.) Assam Agricultural University, Jorhat, 1996, First Class.

Higher Secondary (Science) 1990, Assam, Jagannath Barooah College, Jorhat, Assam, First Division.

Matriculation 1988, Balya Bhavan, Jorhat, Assam, First Division.

Membership

Life Member NORTH-EAST BIOTECHNOLOGICAL ASSOCIATION
 
Projects

1. Synthesis of biodegradable nanocarriers for targeted drug delivery.
    Funded by DBT, Govt. Of India (2006-2009)

2. Electrospun Nanofiber Scaffolds for Hepatic Tissue Engineering.
    Funded by DBT, Govt. Of India (2006-2009)

3. Nanoparticle mediated targeted siRNA delivery to cancer cell lines.
    Funded by DST, Govt. Of India (2007-2010)

4. Glucose sensor based on evanescent wave induced fluorescence spectroscopy.
    (As Co PI with Dr. S.K. Khijwania, Dept. of Physics, IITG). Funded by Dept. of Atomic Energy.

5. Enzymatic Biofuel Cell for Biomedical applications.
    (As Co. Investigator with Dr. P. Goswami). Funded by DBT, Govt. Of India (2007-2009).
 
6. Development of Enzyme Electrode for the Construction of Cholesterol Biosensor.
    (As Co-PI with Dr. Pranab Goswami as PI). Funded by CSIR (2007-2010)
 
Publications


List of Publications in Journals           

             2012

  1. Babu P J, Saranya S, Sharma P, Bora U (2012) UV Light mediated synthesis of gold nanoparticles using ethonolic leaf extract of Bocopa monnieri. (Accepted in Material Letters).
  2. Babu P J, Sharma P, Bora U (2012) Sapindus mukorossi aqueous fruit extract as reducing, capping and dispersing agents in synthesis of gold nanoparticles. (Accepted in Micro and Nano Letters).
  3. Das RK, Gogoi N, Babu PJ, Sharma P, Mahanta C, Bora U (2012) The Synthesis of gold nanoparticles using Amaranthus spinosus leaf extract and study of their optical properties (Accepted in Advanced Materials Physics and Chemistry)
  4. Kumar A and Bora U (2012) Interactions of curcumin derivatives and its metal complexes with nucleic acids and their implications. (Accepted in Mini Reviews in Medicinal Chemistry)
  5. Das RK, Babu PJ, Gogoi N, Sharma P, Bora U (2012) Microwave mediated rapid synthesis of gold nanoparticles using Calotropis procera latex and study of optical properties. ISRN Nanomaterials 2012: 1–6.
  6. Kumar A and Bora U (2012) Molecular docking studies on inhibition of Stat3 dimerization by curcumin natural derivatives and its conjugates with amino acids. Bioinformation 8(20): 988-993.
  7. Babu PJ, Sharma P, Sibyala S, Tamuli R, Bora U (2012) Piper betle-mediated green synthesis of biocompatible gold nanoparticles. International Nano Letters 2:18-27    
  8. Babu PJ, Sibyala S, Sharma P, Tamuli R, Bora U (2012) Gold nanoparticles: sonocatalytic synthesis using ethanolic extract of Andrographis  aniculata and functionalization with polycaprolactone–gelatin composites. Front. Mater. Sci. 6(3), 236–249
  9. Sett A, Das S, Sharma P, Bora U. (2012) Aptasensors in Health, Environment and      Food Safety Monitoring.  Open Journal of Applied Biosensor (1) 9-19
  10. Nahar P, Bora U, Sharma G.L., Kannoujia DK (2012) Microwave-mediated enzyme-linked immunosorbent assay procedure, Analytical Biochemistry, 421 (2), 764-766.
  11. Kasoju N, Bora U (2012) Silk fibroin based biomimetic artificial extracellular matrix for hepatic tissue engineering applications. Biomed. Mater (7) 045004-16.
  12. Moirangthem D, Talukdar NC, Kasoju N, Das RK, Bora U (2012) Antioxidant, antibacterial, cytotoxic and apoptotic activity of extracts of Cephalotaxus griffithii Hook. f. (stem bark). BMC Complementary and Alternative Medicine 2012, 12-30
  13. Moirangthem D, Talukdar NC, Kasoju N, Bora U (2012) Differential effects of Oroxylum indicum bark solvent extracts: total phenolic and flavonoid content, antioxidant, antimicrobial, cytotoxic and apoptotic study. Cytotechnology (available online).
  14. Kasoju, N, Bora U (2012) Silk fibroin in tissue engineering. Advanced Healthcare Materials 1 (4), 393–412.
  15. Kasoju, N, Bora U (2012) Fabrication and charecterization of curcumin releasing silk fibroin scaffold. Journal of Biomedical Materials Research: Part B – Applied Biomaterials 100 (7), 1854–1866, October 2012

     2011
  16. Bora U, Kannoujia DK, Kumar S, Sharma P, Nahar P (2011) Photochemical activation of polyethylene glycol and its application in pegylation of protein,  Process Biochemistry, 46 (6), 1380-1383.
  17. Kumar A, Bora U (2011) In silico inhibition studies of NF-kB p50 subunit by curcumin and its natural derivatives, Medicinal Chemistry Research (DOI 10.1007/s00044-011-9873-0)
  18. Sahu A, Kasoju N, Goswami P, Bora U (2011) Encapsulation of Curcumin in Pluronic Block Copolymer, Journal of Biomaterials Applications, 25 (6), 619-639.
  19. Kasoju N, Bora U (2011) Functional Biomimetic Scaffolds in Tissue Engineering: Towards Development of a Functional Tissue Analogue, Int. J. Biol. Sc.Engg. 2 (1), 56-59
  20. Babu PJ, Das RK,  Kumar A, Bora U (2011) Microwave-Mediated Synthesis of Gold Nanoparticles Using Coconut Water International Journal of Green Nanotechnology: Biomedicine, 3 (1), 13-21.
  21. Das RK, Sharma P, Nahar P, Bora U (2011) Synthesis of gold nanoparticles using aqueous extract of Calotropis procera latex,  Materials Letters, 65 (4), 610-61.
  22. Das RK, Gogoi N and Bora U (2011) Green synthesis of gold nanoparticles using Nyctanthes arbortristis flower extract, Bioprocess and Biosystems Engineering, 34 (5), 615-619.
  23. Babu PJ, Sharma P, Kalita MC, Bora U (2011) Green synthesis of biocompatible gold nanoparticles using Fagopyrum esculentum leaf extract. Frontiers in Materials Scence 2011, 5(4): 379–387.
  24. Das RK, Sett A, Kasoju N, Sumithra B, Bora B (2011) Encapsulation of curcumin into poly-ε-caprolactone nanoparticles and its physicochemical characterization, International Journal of Biological Sciences and Engineering 2 (1), 1-8.
  25. Saxena U, Das M, Ahmed M, Barbora L, Borthakur M, Verma A, Bora U and Goswami P (2011) Multiwalled Carbon Nanotube-Based Enzyme Electrode for Total Cholesterol Estimation in Human Serum, Journal of Experimental Nanoscience, 6 (1), 84-95

     2010
  26. Patel S, Kasoju N, Bora U, Goyal A (2010) Structural analysis and biomedical applications of dextran produced by a new isolate Pediococcus pentosaceus screened from biodiversity hot spot Assam, Bioresource Technology, 101 (17), 6852-6855.]
  27. Srivastava P, Kasoju N, Bora U, Chaturvedi R (2010) Accumulation of Betulinic, Oleanolic, and Ursolic acids in In vitro Cell Cultures of Lantana camara L. and their Significant Cytotoxic Effects on HeLa Cell lines, Biotechnology and Bioprocess Engineering, 15, 1038-1046.
  28. Das RK, Kasoju N, Bora U (2010) Encapsulation of Curcumin in Alginate-Chitosan-Pluronic Composite Nanoparticles for Delivery to Cancer cells, Nanomedicine: Nanotechnology, Biology and Medicine, 6 (1), 153-160.
  29. Kasoju N, Bora U (2010) Antheraea assama Silk Fibroin‐Based Functional Scaffold with Enhanced Blood Compatibility for Tissue Engineering Applications, Advanced Engineering Materials, 12 (5), B139–B147.
  30. Das RK, Borthakur BB, Bora U (2010) Green synthesis of gold nanoparticles using ethanolic leaf extract of Centella asiatica  Materials Letters, 64 (13), 1445-1447.
  31. Ryakala VK, Ali SS, Sharanabasava H, Hasin N, Sharma P, Bora U (2010) Ethnobotany of Plants Used to Cure Diabetes by the People of North East India. Medicinal Aromatic Plant Sci. Biotech. 4 (1), 64-68
  32. Kasoju N, Bora U (2010) Improving the standards of scientific publishing in India The Indian Journal of Medical Research, 132 (5),  523-524.
  33. Kasoju N, Ali SS, Sahu A, Das RK, Babu PJ and Bora U (2010) Surface functionalization of chitosan – PEO electrospun nanofibrous scaffold. Asian Chitin Journal, Vol. 6, Issue 1, pp. 41-46.
  34. Babu PJ, Sharma P,  Borthakur BB, Das RK,  Nahar P and Bora U (2010) Synthesis of Gold Nanoparticles Using Mentha arvensis Leaf Extract, International Journal of Green Nanotechnology: Physics and Chemistry, 2 (2), P62-P68

     2009
  35. Sahu A, Goswami P, Bora U (2009) Microwave mediated rapid synthesis of chitosan, Journal of Materials Science: Materials in Medicine, 20 (1), 171-5.
  36. Kasoju N, Bhonde RR, Bora U (2009) Fabrication of a novel micro-nano fibrous nonwoven scaffold with Antheraea assama silk fibroin for use in tissue engineering, Materials Letter, 63 (28), 2466-2469.
  37. Kasoju N, Bhonde RR, Bora U (2009) Preparation and characterization of Antheraea assama silk fibroin based novel non-woven scaffold for tissue engineering applications, Journal of Tissue Engineering and Regenerative Medicine, 3 (7), 539-52.
  38. Kasoju N, Bora DK, Bhonde RR, Bora U (2009) Synthesis, characterization and application of novel biodegradable self assembled 2 - (N-phthalimido) ethyl - palmitate nanoparticles for cancer therapy, Journal of  Nanoparticle  Research, 12 (3), 801-810.
  39. Srivastava P, Kasoju N, Bora U, Chaturvedi R (2009) Dedifferentiation of leaf explants and cytotoxic activity of an aqueous extract of cell cultures of Lantana camara L., Plant Cell Tissue and  Organ Culture, 99, 1-7
  40. Kasoju N, Ali SS, Dubey VK, Bora U (2009) Exploiting the potential of collagen as a natural biomaterial for drug delivery, Journal of Proteins and Proteomics, 1 (1), 31-36.
  41. Bora DK, Das RK, Kasoju N, Bora U (2009) preparation and charecterization of chitosan membrane activated by carbonyl diimidazole and its application for covalent immobilization of proteins, Asian Chitin Journal, 5 (1), 87-92.
  42. Shukla AK, Bora U, Dubey VK (2009) Functional Adaptations in Fibroblast Growth Factor (FGFs) Family, Journal of Proteins and Proteomics, 1 (1), 11-13.

     2008
  43. Sahu A, Bora U, Kasoju N, Goswami P (2008) Synthesis of novel biodegradable and self-assembling methoxy poly(ethylene glycol)-palmitate nanocarrier for curcumin delivery to cancer cells, Acta Biomaterelia, 4 (6), 1752-61.
  44. Sahu A, Kasoju N, Bora U (2008) Fluorescence study of the curcumin-casein micelle complexation and its application as a drug nanocarrier to cancer cells, Biomacromolecules, 9 (10), 2905-2912.
  45. Ali SS, Kasoju N, Luthra A, Singh A, Sharanabasava H, Sahu A, Bora U (2008) Indian medicinal herbs as sources of antioxidants., Food Research International, 41, 1-15.
  46. Ali SS, Kasoju N, Sahu A, Bora DK, Bora U (2008) Removal of coomassie brilliant blue from laboratory wastewater with chitosan beads, Asian Chitin Journal, 4, 75-84.

     2007
  47. Bora U, Sahu A, Saikia AP, Ryakala VK, Goswami P (2007) Medicinal plants used by the people of Northeast India for curing malaria, Phytotherapy Research, 21 (8), 800-804.

     2006
  48. Bora U, Sharma P, Kannan K, Nahar P (2006) Photoreactive cellulose membrane--A novel matrix for covalent immobilization of biomolecules, Journal of Biotechnology, 126 (2), 220-229.
  49. Bora U, Sharma P, Kumar S, Kannan K, Nahar P (2006) Photochemical activation of a polycarbonate surface for covalent immobilization of a protein ligand, Talanta, 70 (3), 624-629.
  50. Saikia AP, Ryakala VK, Sharma P, Goswami P, Bora U (2006) Ethnobotany of medicinal plants used by Assamese people for various skin ailments and cosmetics, Journal of Ethnopharmacology, 106 (2), 149-57.

    2005
  51. Bora U, Kannan K, Nahar P (2005) A simple method for functionalization of cellulose membrane for covalent immobilization of biomolecules, Journal of Membrane Science, 250, 215-222.

     2004
  52. Bora U, Kannan K, Nahar P (2004) Heat-mediated enzyme-linked immunosorbent assay procedure on a photoactivated surface, Journal of  Immunological Methods, 293 (1-2), 43-50.
  53. Nahar P, Bora U (2004) Microwave-mediated rapid immobilization of enzymes onto an activated surface through covalent bonding, Anaytical Biochemistry, 328 (1), 81-3.

     2002
  54. Bora U, Chugh L, Nahar P (2002) Covalent immobilization of proteins onto photoactivated polystyrene microtiter plates for enzyme-linked immunosorbent assay procedures, Journal of  Immunological Methods, 268 (2), 171-7.

     2000
  55. Sen P, Bora U, Ray BK, Deka PC (2000) Electrophoretic pattern of leaf proteins in Camellia spp, Journal Interacademia, 4, 234-241.
  56. Sen P, Bora U, Ray BK, Deka PC (2000) Isozyme charecterization in Camellia spp, Crop Research, 19, 519.

International Patents:

1.    Nahar P, Bora U and Sharma G.L.  Rapid Method for Enzyme-Linked Immunosorbent Assay, US patent no. 6498016 (2002).

2.    Nahar P, Bora U and Sharma G.L.  Rapid Method for Enzyme-Linked Immunosorbent Assay, EP patent no. 1309864 (2005).

3.    Nahar P, Bora U and Sharma G.L.  Rapid Method for Enzyme-Linked Immunosorbent Assay, AU patent no. 2001218830 (2005).

4.    Nahar P, Bora U and Sharma G.L.  Rapid Method for Enzyme-Linked Immunosorbent Assay,   Russian patent no. 2249218 (2005).

5.    Nahar P and Bora U.  Rapid Heat-Mediated Method for Enzyme Linked Immunosorbent Assay Procedure. EP 1608971 (13.2.08)

·                 6.    Nahar P and Bora U.  Rapid Heat-Mediated Method for Enzyme Linked Immunosorbent Assay Procedure, Russian patent (appl.# 2005133445)
                Allowed  for Grant 2007.
 
Students & Staff

Ph.D. Student

1. Abhishek Sahu
2. Naresh Kosoju
3. Punuri Jayshekhara Babu 

Project Staff

 1. Shahin Sharif Ali, JRF(Ex.)
2. Debojeet Bora, JRF
3. Ratul Das, JRF 

BTP Student

 1. Nishant Bithal 2005-06
2. Neelakshi Das 2006-07
3. Venkat K. Ryakala 2006-07
4. Jaideepak Parvatiana 2007-08
5. Uday Kumar 2008-09

 

Updated on 16th Nov 2012